Acta Neurochirurgica

, Volume 150, Issue 5, pp 491–496 | Cite as

Atypical teratoid/rhabdoid tumour in sella turcica in an adult

  • K. AritaEmail author
  • K. Sugiyama
  • T. Sano
  • H. Oka
Case Report


Although atypical teratoid rhabdoid tumours preferentially arise in the posterior fossa of infants, we encountered a 56 year old woman with an atypical teratoid rhabdoid tumour located in the sella. She presented with right abducent and oculomotor nerve paresis. Magnetic resonance imaging demonstrated an intrasellar tumour impinging on the right cavernous sinus. Microscopically, the tumour was composed of cells with rhabdoid features; we observed atypia, eccentric nuclei, and intracytoplasmic inclusion bodies. The Ki-67 labeling index was around 30%. The tumour cells were positive for vimentin, epithelial membrane antigen, and neurofilament, but negative for INI1. Despite extended local brain and whole-spine irradiation she died of neural axis dissemination.

Keywords: Atypical; teratoid rhabdoid tumour; sella turcica; INI1. 


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  1. 1.Department of Neurosurgery, Graduate School of Medical and Dental SciencesKagoshima UniversityKagoshimaJapan
  2. 2.Department of Neurosurgery, Graduate School of Biomedical ScienceHiroshima UniversityHiroshimaJapan
  3. 3.Department of Human Pathology, Institute of Health BioscienceUniversity of Tokushima Graduate SchoolTokushimaJapan
  4. 4.Department of NeurosurgeryKitasato University School of MedicineSagamiharaJapan

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