Acta Neurochirurgica

, Volume 147, Issue 9, pp 965–972

Microcystic meningiomas: radiological characteristics of 16 cases

  • S. H. Paek
  • S. H. Kim
  • K. H. Chang
  • C.-K. Park
  • J. E. Kim
  • D. G. Kim
  • S.-H. Park
  • H.-W. Jung
Clinical Article

Summary

Background. As a rare subtype of meningioma, only a few reports deal with radiological characteristics of microcystic meningiomas and the problem remains controversial. The authors have analyzed the radiological findings of a series of microcystic meningiomas with a special focus on magnetic resonance images (MRI) and conventional angiography.

Method. Sixteen patients of histologically proven microcystic meningiomas were included. Analysis of preoperative MRI including signal intensity characteristics, enhancement patterns and peritumoural edema were performed and correlated with angiographic and histological findings. Peritumoural edema was graded using edema index (EI) which was defined as the ratio of VE/VT.

Findings. The tumours were uniformly visualized as a high-signal mass lesion in T2-weighted images and as a low-signal mass lesion in T1-weighted images regardless of tumour vascularity shown by angiography. T2-weighted images revealed that peritumoural brain edema was severe in 11, moderate in 1, mild in 2 and negligible in 2 patients and this was closely related to the co-existence of irregular tumour marginal enhancement. However, other features failed to distinguish these lesions from other subtypes of meningioma.

Conclusions. The cases presented demonstrate that characteristic MRI findings suggestive of microcystic meningiomas are; (1) low signal intensity mass in T1- and high signal intensity mass in T2-weighted images; (2) high incidence of peritumoural edema.

Keywords: Microcystic meningioma; peritumoural edema; radiological characteristics; signal intensity. 

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References

  1. Bromley, PJ, Grymaloski, MR, Zetler, PJ 1996CT appearance of microcystic meningioma.J Comput Assist Tomogr20570572CrossRefPubMedGoogle Scholar
  2. Christov, C, Lechapt-Zalcman, E, Adle-Biassette, H, Nachev, S, Gherardi, RK 1999Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptor flt-1 in microcystic meningiomas.Acta Neuropathol (Berl)98414420CrossRefGoogle Scholar
  3. Kaplan, RD, Coons, S, Drayer, BP, Bird, CR, Johnson, PC 1992MR characteristics of meningioma subtypes at 1.5 tesla.Comput Assist Tomogr16366371Google Scholar
  4. Kleihues, P, Burger, PC, Scheithauer, BW 1993The new WHO classification of brain tumours.Brain Pathol3255268PubMedGoogle Scholar
  5. Kubota, Y, Ueda, T, Kagawa, Y, Sakai, N, Hara, A 1997Microcystic meningioma without enhancement on neuroimaging-case report.Neurol Med Chir (Tokyo)37407410Google Scholar
  6. Kuchna, I, Matyja, E, Wierzba-Bobrowicz, T, Mazurowski, W 1994Microcystic meningioma – a rarely occurring morphological variant of meningioma.Folia Neuropathol32259263PubMedGoogle Scholar
  7. Masson P (1956) Les meningiomes: les tumeurs humaines, 2nd edn. Librairie Maloine, Paris, pp 977–988Google Scholar
  8. Meyronet, D, Mohamedi, R, Gentil-Perret, A, Barral, FG, Brunon, J, Mosnier, JF 2003Microcystic meningiomas: comparison of histology and computed tomography.Rev Neurol (Paris)1595055Google Scholar
  9. Michaud, J, Gagne, F 1983Microcystic meningioma. Clinicopathologic report of eight cases.Arch Pathol Lab Med1077580PubMedGoogle Scholar
  10. Nishio, S, Takeshita, I, Fukui, M 1994Microcystic meningioma: tumors of arachnoid cap vs trabecular cells.Clin Neuropathol13197203PubMedGoogle Scholar
  11. Nishio, S, Takeshita, I, Morioka, T, Fukui, M 1994Microcystic meningioma: clinicopathological features of 6 cases.Neurol Res16251256PubMedGoogle Scholar
  12. Paek, SH, Kim, CY, Kim, YY, Park, IA, Kim, MS, Kim, DG, Jung, HW 2002Correlation of clinical and biological parameters with peritumoral edema in meningioma.J Neurooncol60235245CrossRefPubMedGoogle Scholar
  13. Paik, SS, Jang, SJ, Park, YW, Hong, EK, Park, MH, Lee, JD 1996Microcystic meningioma. A case report.J Korean Med Sci11540543PubMedGoogle Scholar
  14. Sakagami, Y, Kudo, H, Kawamura, A, Mimura, K, Tamaki, N 1998Microcystic meningioma with intratumoral hemorrhage: a case report.Jpn J Neurosurg (Tokyo)7648652Google Scholar
  15. Scheithauer, BW 1990Tumors of the meninges: proposed modifications of the World Health Organization classification.Acta Neuropathol (Berl)80343354CrossRefGoogle Scholar
  16. Shimoji, K, Yasuma, Y, Mori, K, Eguchi, M, Maeda, M 1999Unique radiological appearance of a microcystic meningioma.Acta Neurochir (Wien)14111191121CrossRefGoogle Scholar
  17. Tamiya, T, Ono, Y, Matsumoto, K, Ohmoto, T 2001Peritumoral brain edema in intracranial meningiomas: effects of radiological and histological factors.Neurosurgery4910461051CrossRefPubMedGoogle Scholar
  18. Yoshioka, H, Hama, S, Taniguchi, E, Sugiyama, K, Arita, K, Kurisu, K 1999Peritumoral brain edema associated with meningioma: influence of vascular endothelial growth factor expression and vascular blood supply.Cancer85936944CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag/Wien 2005

Authors and Affiliations

  • S. H. Paek
    • 1
  • S. H. Kim
    • 1
  • K. H. Chang
    • 2
  • C.-K. Park
    • 1
  • J. E. Kim
    • 1
  • D. G. Kim
    • 1
  • S.-H. Park
    • 3
  • H.-W. Jung
    • 1
  1. 1.Department of Neurosurgery and Clinical Research InstituteSeoul National University College of Medicine, Seoul National University HospitalSeoulKorea
  2. 2.Department of RadiologySeoul National University College of Medicine, Seoul National University HospitalSeoulKorea
  3. 3.Department of PathologySeoul National University College of Medicine, Seoul National University HospitalSeoulKorea

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