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Microchimica Acta

, 187:12 | Cite as

Fluorometric determination of fipronil by integrating the advantages of molecularly imprinted silica and carbon quantum dots

  • Chunhui Yang
  • Lihong Wang
  • Zhen Zhang
  • Yujie Chen
  • Qiliang DengEmail author
  • Shuo WangEmail author
Original Paper
  • 25 Downloads

Abstract

A fluorometric method is described for the determination of fipronil, a frequently-used insecticide. It exploits the blue fluorescence of carbon quantum dots (CQDs) and the selectivity of molecularly imprinted silica (MIS). The MIS was prepared via the sol-gel method by using fipronil as the template, 3-aminopropyltriethoxysilane as functional monomer, and tetraethoxysilane as cross-linker in the presence of CQDs. The blue fluorescence of the CQD@MIS, with excitation/emission peaks at 340/422 nm, is quenched by fipronil. The assay works in the 0. 70 pM to 47 μM fipronil concentration range, and the limit of detection is 19 pM. The method was successfully applied to the quantitation of fipronil in spiked eggs, milk, and tap water. Recoveries between 83.8 and 114.0% were achieved. The corresponding relative standard deviations (RSD) are less than 6.67%.

Graphical abstract

Schematic representation of a high sensitivite and selectivite fluorescence nanoprobe constructed by combining the excellent fluorescence property of carbon quantum dots and the predicted selectivity of molecularly imprinted silica. It was applied to analyze fipronil in egg, milk and tap water, respectively.

Keywords

Food safety Fluorescence quenching Milk Analysis Egg Analysis Insecticide 

Notes

Acknowledgments

The authors are grateful for the financial support provided by the Ministry of Science and Technology of China (Project No.2016YFD0401101) and the National Natural Science Foundation of China (Project No.21375094).

Supplementary material

604_2019_4005_MOESM1_ESM.doc (23.9 mb)
ESM 1 (DOC 24473 kb)

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.College of Chemical Engineering and Materials ScienceTianjin University of Science and TechnologyTianjinChina
  2. 2.Tianjin Key Laboratory of Food Science and Health, School of MedicineNankai UniversityTianjinChina

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