Carbon fibers coated with urchin-like copper sulfide for nonenzymatic voltammetric sensing of glucose
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Urchin-like CuS was grown on xanthan gum-derived carbon nanofibers to obtain a sensor for enzyme-free electrochemical sensing of glucose. The unique nanostructure of the sensor provides a large specific surface, more electrocatalytically active sites, and high electrical conductivity. The voltammetric response to glucose, best measured at around 57 mV (vs. Ag/AgCl (E/V)) in 0.1 M NaOH solution, covers two linear ranges, one from 0.1–125 μM, another from 0.16 to 1.2 mM. The sensitivity is quite high (23.7 μA mM−1 cm−2), and the detection limit is low (19 nM at S/N = 3). The sensor has high selectivity against potentially interfering molecules such as fructose, appreciable operational stability, excellent durability, and good repeatability (with relative standard deviations of 2.3%). It was successfully applied to the determination of glucose in diluted serum samples.
KeywordsXanthan gum derived carbon Copper sulfide Electrochemical detection Enzyme-free biosensor Human blood serum
This project was supported by the Ministry of Science and Technology (MOST 106-2113-M-027-003), Taiwan, ROC.
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Conflict of interest
There are no conflicts of interest to declare.
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