Microchimica Acta

, 186:696 | Cite as

Novel manganese(II)-based metal-organic gels: synthesis, characterization and application to chemiluminescent sensing of hydrogen peroxide and glucose

  • Jiaqi Yu
  • Mengya Cao
  • Hao Wang
  • Yongxin LiEmail author
Original Paper


A metal-organic gel (MOG) was synthesized that is composed of manganese(II) as the central ion and 1,10-phenanthroline-2,9-dicarboxylic acid as the ligand. The resulting MOG exhibits excellent activity for catalyzing the chemiluminescence (CL) of the luminol/hydrogen peroxide system. The CL system was characterized by CL spectra, UV-vis absorption spectra and by studying potential interferences by common radical scavengers. The CL reaction was exploited in a new scheme for the determination of hydrogen peroxide. CL intensity increases linearly in the 0.4 μM ~ 3 mM hydrogen peroxide concentration range, and the limit of detection (LOD) is 0.12 μM. The method was extended to an enzymatic assay for glucose by using glucose oxidase and by measurement of the enzymatically formed hydrogen peroxide. The assay works in the 0.2 μM ~ 3 mM glucose concentration range, and the LOD is 0.08 μM.

Graphical abstract

Schematic representation of the synthesized Mn-containing MOGs catalyzing luminol-hydrogen peroxide chemiluminescent reaction, which can be used to establish a new CL method for the detection of hydrogen peroxide and glucose.


Metal−organic gels Luminol Hydrogen peroxide Glucose Chemiluminescence 



This work is financially supported by the National Natural Science Foundation of China (No.21775003, No.21375002), and the Foundation for Innovation Team of Bioanalytical Chemistry of Anhui Province.

Compliance with ethical standards

Conflict of interest

The author(s) declare that they have no competing interests.

Supplementary material

604_2019_3808_MOESM1_ESM.docx (51 kb)
ESM 1 (DOCX 50 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Anhui Key Laboratory of Chemo/Biosensing, College of Chemistry and Materials ScienceAnhui Normal UniversityWuhuPeople’s Republic of China

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