A nanocomposite consisting of gold nanobipyramids and multiwalled carbon nanotubes for amperometric nonenzymatic sensing of glucose and hydrogen peroxide
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Gold nanobipyramids were synthesized by a seed-mediated growth method and then supported by multi-walled carbon nanotubes (denoted as AuNBP/MWCNTs). The electrocatalytic activity of the AuNBP/MWCNTs on a glassy carbon electrode (GCE) towards direct glucose oxidation and hydrogen peroxide reduction was superior to that of AuNBPs and MWCNTs. The modified GCE, operated at a typical working voltage of +0.15 V (vs. SCE) and in 0.1 M NaOH solution, exhibits a linear response in the 10 μM to 36.7 mM glucose concentration range with a 3.0 μM detection limit (at S/N = 3) and a sensitivity of 101.2 μA mM−1 cm−2. It also demonstrates good sensitivity towards hydrogen peroxide in at pH 7 solution at a working potential of −0.50 V (vs. SCE), with a linear response range from 5.0 μM to 47.3 mM, a sensitivity of 170.6 μA mM−1 cm−2 and a detection limit of 1.5 μM.
KeywordsNanomaterials Electrocatalyst Electrochemical sensor Non-enzymatic sensor Cyclic voltammetry Chronoamperometry Real sample analysis
This work was partially supported by the Natural Science Foundation of China (81573110, 31270958), the Chinese National 863 plan (2012AA02A407), the Natural Science Foundation of Zhejiang Province (LY14H190004, LY13H100003, LY15H160066), the Key Science and Technology Innovation Team of Zhejiang Province, Wenzhou Municipal Research Program (Y20160009, Y20160074), and Natural Science Foundation of Zhejiang Province (LQ17B030003).
Compliance with ethical standards
The author(s) declare that they have no competing interests.
- 5.Kangkamano T, Numnuam A, Limbut W, Kanatharana P, Thavarungkul P (2017) Chitosan Cryogel with embedded gold nanoparticles decorated multiwalled carbon nanotubes modified electrode for highly sensitive flow based non-enzymatic glucose sensor. Sensors Actuators B Chem 246:854–863. https://doi.org/10.1016/j.snb.2017.02.105 CrossRefGoogle Scholar
- 7.Luo Y, Kong FY, Li C, Shi JJ, Lv WX, Wang W (2016) One-pot preparation of reduced graphene oxide-carbon nanotube decorated with Au nanoparticles based on protein for non-enzymatic electrochemical sensing of glucose. Sensors Actuators B Chem 234:625–632. https://doi.org/10.1016/j.snb.2016.05.046 CrossRefGoogle Scholar
- 9.Tang YR, Liu Q, Yang X, Wei M, Zhang MX (2017) Copper oxide coated gold nanorods like a film: A facile route to nanocomposites for electrochemical application. J Electroanal Chem 806:8–14. https://doi.org/10.1016/j.jelechem.2017.10.032
- 16.He ZY, Zang SA, Liu Y, He Y, Lei HT (2015) A multi-walled carbon nanotubes-poly(L-lysine) modified enantioselective immunosensor for ofloxacin by using multi-enzyme-labeled gold nanoflower as signal enhancer. Biosens Bioelectron 73:85–92. https://doi.org/10.1016/j.bios.2015.05.054 CrossRefPubMedGoogle Scholar
- 23.Nantaphol S, Watanabe T, Nomura N, Siangproh W, Chailapakul O, Einaga Y (2017) Bimetallic Pt-Au nanocatalysts electrochemically deposited on boron-doped diamond electrodes for nonenzymatic glucose detection. Biosens Bioelectron 98:76–82. https://doi.org/10.1016/j.bios.2017.06.034 CrossRefPubMedGoogle Scholar
- 27.Łuczak T, Bełtowska-Brzezinska M (2011) Gold electrodes modified with gold nanoparticles and thio compounds for electrochemical sensing of dopamine alone and in presence of potential interferents. A comparative study. Microchim Acta 174:19–30. https://doi.org/10.1007/s00604-011-0614-3 CrossRefGoogle Scholar