Electrochemical dopamine sensor based on the use of a thermosensitive polymer and an nanocomposite prepared from multiwalled carbon nanotubes and graphene oxide
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An electrochemical dopamine sensor with a temperature-controlled switch was constructed by using a mixture of thermo-sensitive block copolymers (type tBA-PDEA-tBA), graphene oxide (GO) and multi-walled carbon nanotubes (MWCNTs). If the temperature is below 26 °C, the polymer on the glassy carbon electrode (GCE) is stretched, the distance between the MWCNTs is large, and the charge transfer resistance (Rct) of the composite also is large. In the presence of dopamine, the electron transfer at the electrode is strongly retarded and in the “off” state. At above 38 °C, the polymer is shrunk and the Rct is much smaller. The presence of dopamine results in a rapid electron transfer at the GCE, and this is referred to as the “on” state. At temperatures between 26 and 38 °C, the polymer shrinks slightly and has a “spring-like” state. There is a linear relationship between the response current (typically measured at a potential as low as 0.16 V vs. Ag/AgCl) and temperature. The response to dopamine is linear in the 0.06 to 4.2 μM and 4.2 to 18.2 μM concentration range, and the detection limit is 42 nM. Conceivably, this approach provides a novel approach towards the design of electrochemical sensors based on the use of thermo-sensitive polymers.
KeywordsN,N-Diethylacrylamide Tert-butyl acrylate Electrochemical “on/off” detection Stimulus-responsive polymer Spring-like sensor Carbon nanomaterials
This research was financially supported by the NSF of China (Grants No. 21874114, 21475114, 21775133 and 31701613), the project of innovation team of the ministry of education (IRT_17R90), the Project of Science and Technology Plan of Hunan Province (2017XK2055), Hunan Provincial Innovation Foundation for Postgraduate (CX2018B364).
Compliance with ethical standards
The author(s) declare that they have no competing interests.
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