A core-shell structured magnetic covalent organic framework (type Fe3O4@COF) as a sorbent for solid-phase extraction of endocrine-disrupting phenols prior to their quantitation by HPLC
- 72 Downloads
A magnetic covalent organic framework (Fe3O4@COF) with core–shell structure was fabricated at room temperature and used as an adsorbent for magnetic solid-phase extraction of polar endocrine-disrupting phenols (4-n-nonylphenol, 4-n-octylphenol, bisphenol A and bisphenol AF). The sorbent was characterized by transmission electron microscopy, FTIR, powder X-ray diffraction and other techniques. The main parameters governing the extraction efficiency were optimized. The phenols were quantified by HPLC with fluorometric detection. The method has attractive features such as low limits of detection (0.08–0.21 ng.mL−1), wide linear ranges (0.5–1000 ng.mL−1), and good repeatability (intra-day: 0.39%–4.99%; inter-day: 1.57%–5.21%). Satisfactory results were obtained when the developed method was applied to determine the four target pollutants in real world drink samples with spiked recoveries over the range of 81.3~118.0%. This indicates that the method is a powerful tool for the enrichment and determination of endocrine-disrupting phenols in drink samples.
KeywordsCore–shell structured magnetic microspheres Fe3O4@COFs Bisphenols 4-n-nonylphenol 4-n-octylphenol Absorption Pretreatment Determination Optimization Drink samples
This work was supported by the National Natural Science Foundation of China (21777089), the Natural Science Foundation of Shandong Province (ZR2018MB040), the Key Research and Development Program of Shandong Province (2017GSF17107 and 2018GSF117036), Shandong Provincial Key Laboratory of Test Technology for Material Chemical Safety (2018SDCLHX001), and the Shandong Province Taishan Scholar Program (ts201712063).
Compliance with ethical standards
The author(s) declare that they have no competing interests.
- 1.Zeng BW, Jiang P (2005) Environmental hormone. Chemical Industry Press, Beijing, pp 1–15Google Scholar
- 2.Du HF, Yan HF (2005) Progress on detection and analysis method of endocrine disrupting compounds. J Hyg Res 34:493–496Google Scholar
- 3.Jin F, Zhang Y, Wang J (2008) Review on advance of phenolic endocrine disrupting chemicals in food. Sci Technol Food Ind 29:263–270Google Scholar
- 35.Herrero-Hernández E, Carabias-Martínez R, Rodríguez-Gonzalo E (2009) Use of a bisphenol-A imprinted polymer as a selective sorbent for the determination of phenols and phenoxyacids in honey by liquid chromatography with diode array and tandem mass spectrometric detection. Anal Chim Acta 650:195–201CrossRefGoogle Scholar