Microchimica Acta

, 185:521 | Cite as

Photoelectrochemical sensing of tannic acid based on the use of TiO2 sensitized with 5-methylphenazinium methosulfate and carboxy-functionalized CdTe quantum dots

  • Fernanda Maria dos Reis Lima
  • André da Silva Freires
  • Neuma das Mercês Pereira
  • Glaura Goulart Silva
  • Cláudia Quintino da Rocha
  • Flavio Santos Damos
  • Rita de Cássia Silva LuzEmail author
Original Paper


The article describes a method for determination of tannic acid in extracts of medicinal plants. Tannic acid (TA) is an antioxidant and has anticancer and antimicrobial properties. Titanium dioxide nanoparticles (TiO2) were co-sensitized with 5-methylphenazinium methosulfate (PMS) and carboxy-functionalized cadmium telluride quantum dots (CdTe QDs), and immobilized on a fluorine-doped tin oxide electrode. The surface morphology and electrochemical properties of the modified electrode were investigated by scanning electron microscopy and amperometry, respectively. A composite consisting of TiO2, PMS and CdTe QDs in a nafion film has a response to TA under LED light higher than that observed for each separate component. Under optimized experimental conditions and at an applied voltage of +0.4 V vs Ag/AgCl, the photoelectrochemical sensor has a linear response in the 0.2 to 200 μmol L−1 TA concentration range and a detection limit of 60 nmol L−1. The sensor was successfully applied to the determination of TA in spiked extracts from three medicinal plants, with recovery values between 98.3 and 103.9 %.

Graphical abstract

Schematic diagram for photoelectrochemical detection of tannic acid based on a fluorine doped tin oxide electrode modified with titanium oxide, 5-methylphenazinium methosulfate and carboxy-functionalized cadmium telluride quantum dots


Photoelectrochemistry LED light Nanoparticles Quantum dots Phenazine Medicinal plants 



The authors are grateful to FAPEMA (PRONEM-00155/16; UNIVERSAL-00927/16; UNIVERSAL-01194/17), CNPq (303525/2016-9; 421139/2016-1; 305680/2015-3;426337/2016-6), and Instituto Nacional de Ciência e Tecnologia em Bioanalítica (465389/2014-7) for financial support. The authors are grateful to the Microscopy Center/UFMG by the SEM images.

Compliance with ethical standards

The author(s) declare that they have no competing interests.

Supplementary material

604_2018_3047_MOESM1_ESM.docx (220 kb)
ESM 1 (DOCX 220 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Fernanda Maria dos Reis Lima
    • 1
  • André da Silva Freires
    • 1
  • Neuma das Mercês Pereira
    • 2
  • Glaura Goulart Silva
    • 2
  • Cláudia Quintino da Rocha
    • 1
  • Flavio Santos Damos
    • 1
  • Rita de Cássia Silva Luz
    • 1
    Email author return OK on get
  1. 1.Department of ChemistryFederal University of MaranhãoSão LuísBrazil
  2. 2.Department of ChemistryFederal University of Minas GeraisBelo HorizonteBrazil

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