Sensing nitric oxide with a carbon nanofiber paste electrode modified with a CTAB and nafion composite
- 261 Downloads
We describe an electrochemical sensor for nitric oxide that was obtained by modifying the surface of a nanofiber carbon paste microelectrode with a film composed of hexadecyl trimethylammonium bromide and nafion. The modified microelectrode displays excellent catalytic activity in the electrochemical oxidation of nitric oxide. The mechanism was studied by scanning electron microscopy and cyclic voltammetry. Under optimal conditions, the oxidation peak current at a working voltage of 0.75 V (vs. SCE) is related to the concentration of nitric oxide in the 2 nM to 0.2 mM range, and the detection limit is as low as 2 nM (at an S/N ratio of 3). The sensor was successfully applied to the determination of nitric oxide released from mouse hepatocytes.
KeywordsHexadecyl trimethyl ammonium bromide Nafion Carbon nanofibers Carbon paste electrode Nitric oxide Mouse hepatocytes
This research is supported by the National Nature Science Foundation of China (Nos. 31070885; 61178087), the Fundamental Research Funds for the Central Universities, South-Central University for Nationalities (Nos. CZY14017; CTZ12001), the Scientific Research Team Project of South-central University for Nationalities (No. XTZ09002).
- 13.Manjunatha JM, Kumara Swamy BE, Gilbert O, Mamatha GP, Sherigara BS (2010) Sensitive voltammetric determination of dopamine at salicylic acid and TX-100, SDS, CTAB Modified Carbon Paste Electrode. Int J Electrochem Sci 5:682–695Google Scholar
- 24.Santos VN, Cabral MF, Ferreira JS, Holanda AKM, Machado SAS, Sousa JR, Lopes LGF, Correia AN, Neto PL (2013) Electrochemical and Monte Carlo studies of self-assembled trans-[Fe(cyclam)(NCS) 2]+ complex ion on gold surface as electrochemical sensor for nitric oxide. Electrochim Acta 91:1–10CrossRefGoogle Scholar