Microchimica Acta

, Volume 178, Issue 1–2, pp 211–219 | Cite as

Electrochemical detection of rutin with a carbon ionic liquid electrode modified by Nafion, graphene oxide and ionic liquid composite

  • Song Hu
  • Huanhuan Zhu
  • Shengyun Liu
  • Jun Xiang
  • Wei Sun
  • Liqi Zhang
Original Paper


We report on a carbon ionic liquid electrode modified with a composite made from Nafion, graphene oxide and ionic liquid, and its application to the sensitive determination of rutin. The modified electrode was characterized by cyclic voltammetry and electrochemical impedance spectroscopy. It shows excellent cyclic voltammetric and differential pulse voltammetric performance due to the presence of nanoscale graphene oxide and the ionic liquid, and their interaction. A pair of well-defined redox peaks of rutin appears at pH 3.0, and the reduction peak current is linearly related to its concentration in the range from 0.08 μM to 0.1 mM with a detection limit of 0.016 μM (at 3σ). The modified electrode displays excellent selectivity and good stability, and was successfully applied to the determination of rutin in tablets with good recovery.


A Nafion, graphene oxide and ionic liquid 1-ethyl-3-methylimidazolium tetrafluoroborate composite was modified on carbon ionic liquid electrode (CILE) for the sensitive detection of rutin.


Graphene oxide Ionic liquid Nafion Carbon ionic liquid electrode Rutin Electrochemistry 



We are grateful to the financial support of the Natural Science Foundation of China (No. 50976043, 21075071, 51076056), the Foundation of State Key Laboratory of Coal Combustion of Huazhong University of Science and Technology (FSKLCC1010) and the Foundation of State Key Laboratory of Clean Energy Utilization of Zhejiang University.


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Song Hu
    • 1
  • Huanhuan Zhu
    • 2
  • Shengyun Liu
    • 2
  • Jun Xiang
    • 1
  • Wei Sun
    • 2
  • Liqi Zhang
    • 1
  1. 1.State Key Laboratory of Coal CombustionHuazhong University of Science and TechnologyWuhanPeople’s Republic of China
  2. 2.Shandong Provincial Key Laboratory of Biochemical Analysis, College of Chemistry and Molecular EngineeringQingdao University of Science and TechnologyQingdaoPeople’s Republic of China

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