Microchimica Acta

, Volume 177, Issue 1–2, pp 129–135 | Cite as

Protein-mediated synthesis of antibacterial silver nanoparticles deposited on titanium dioxide nanotube arrays

Original Paper


We report on an effective route to decorate titanium nanotube arrays (TiNT) with silver nanoparticles (AgNPs). In this method, surface-adsorbed antibody molecules serve as templates to bind silver ions by electrostatic interaction. The photocatalytic activity of the TiNT under UV irradiation causes the photoreduction of AgNPs to occur, and the biological template is decomposed simultaneously. This route also was successfuly applied to gold nanoparticles (starting from negatively charged metallic precursor ions). Compared to undecorated samples, the AgNPs/TiNT samples under visible light display a much higher antibacterial activity against Escherichia coli.


An effective protein-mediated route to decorate Ag nanoparticles (AgNPs) in TiO2 nanotube arrays (TiNT) is reported. The photocatalytic activity of the TiNT under UV irradiation causes the photoreduction of AgNPs to occur, and the biological template is decomposed simultaneously. Compared to undecorated samples, the AgNPs/TiNT samples under visible light display a much higher antibacterial activity against Escherichia coli.


Protein-mediated synthesis TiO2 nanutube Ag nanoparticles Photocatalysis Biological template Antibacterial 

Supplementary material

604_2012_769_MOESM1_ESM.doc (2.6 mb)
ESM 1(DOC 2647 kb)


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.College of SciencesNortheastern UniversityShenyangChina
  2. 2.Department of Physics and EnergyUniversity of LimerickLimerickIreland
  3. 3.Institute of Physical ChemistryPolish Academy of SciencesWarsawPoland

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