Enzyme-free amperometric sensing of glucose using Cu-CuO nanowire composites
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A non-enzymatic amperometric glucose is reported that is based on an glassy carbon electrode modified with a Cu-CuO nanowire (NW) composite. The morphology and the composition of the nanowire were characterized by scanning electron microscopy and X-ray diffraction, respectively. The modified electrode efficiently catalyzes the oxidation of glucose at less-positive potential (0.30 V) in 0.10 M NaOH solution in the absence of any enzymes or redox mediators. The sensor was successfully used for the amperometric sensing of glucose. Linear response was obtained over the concentration range from 0.1 to 12 mM. The common interfering agents ascorbic acid and uric acid do not interfere with the determination of glucose. The modified electrode features high sensitivity, low working potential, excellent stability, and fast amperometric sensing of glucose. Thus it is promising for the future development of non-enzymatic glucose sensors.
KeywordsCuO nanowire Glucose Electrocatalysis Enzyme-free Amperometric detection
This work was supported by the National Natural Science Foundation of China (No.20675001, 20901003), Anhui Key Laboratory of Controllable Chemistry Reaction & Material Chemical Engineering, the Young Teacher Program of Anhui Normal University (2009xqnzc19), and the Natural Science Foundation of Educational Department of Anhui Province (No. KJ2008B167, No. KJ2009B013Z).
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