Microchimica Acta

, Volume 160, Issue 3, pp 375–383 | Cite as

Silica coated quantum dots: a new tool for electrochemical and optical glucose detection

  • Sara Cavaliere-Jaricot
  • Masih Darbandi
  • Erol Kuçur
  • Thomas Nann
Original Paper
First Online:
Received:
Accepted:

Abstract.

The application of silica coated quantum dots (QDs@SiO2) in glucose detection in combination with glucose oxidase is reported. The high specific surface area of such particles can be exploited to immobilise a greater amount of the enzyme on a modified electrode. In addition to this electrochemical method, we report here an indirect optical technique based on the photoluminescence quenching of QDs by hydrogen peroxide produced during glucose oxidation. The results obtained with these two different detection methodologies are compared.

Key words: Silica coated quantum dots; cyclic voltammetry; glucose oxidation; nanotechnology; photoluminescence 
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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Sara Cavaliere-Jaricot
    • 1
  • Masih Darbandi
    • 1
  • Erol Kuçur
    • 1
  • Thomas Nann
    • 2
  1. 1.Freiburg Materials Research Centre (FMF)Albert-Ludwig University FreiburgFreiburgGermany
  2. 2.School of Chemical Sciences and PharmacyUniversity of East Anglia (UEA)NorwichUnited Kingdom

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