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Impact of postoperative mean arterial pressure on the incidence of postoperative complications after hepatic resection for primary liver malignancy

  • Masataka AmisakiEmail author
  • Takuki Yagyu
  • Ei Uchinaka
  • Masaki Morimoto
  • Naruo Tokuyasu
  • Teruhisa Sakamoto
  • Soichiro Honjo
  • Hiroaki Saito
  • Yoshiyuki Fujiwara
Original Article
  • 7 Downloads

Abstract

Purpose

We conducted this study to evaluate the impact of the postoperative mean arterial pressure (MAP) on surgical complications after hepatic resection.

Methods

The subjects of this study were 199 patients who underwent hepatic resection for primary liver malignancy between 2004 and 2013. A clinically relevant postoperative complication was defined as a Clavien–Dindo grade ≥ III complication.

Results

Based on an MAP cut-off value of 81.1 mmHg, the patients were grouped as follows: low MAP on both postoperative days (PODs) 1 and 2 (continuously low MAP), normal MAP on both PODs 1 and 2 (normal MAP), and others (transiently low MAP). The continuously low MAP group had the highest incidence of complications and the normal MAP group had the lowest incidence of complications compared with the expected incidence for this cohort (p < 0.01 and p = 0.01, respectively). Multivariate analysis revealed that both a continuously and transiently low MAP were independent predictors of postoperative complications (p = 0.03 and p < 0.01, respectively). Among the subtypes of complications, a low MAP had a significant relationship with ascites/pleural effusion and respiratory complications (p < 0.01 and p = 0.03, respectively).

Conclusions

A low MAP on POD 1 and/or 2 is an independent predictor of postoperative complications.

Keywords

Liver Resection Postoperative complication Blood pressure 

Notes

Compliance with ethical standards

Conflict of interest

We have no conflicts of interest to declare.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Masataka Amisaki
    • 1
    Email author
  • Takuki Yagyu
    • 1
  • Ei Uchinaka
    • 1
  • Masaki Morimoto
    • 1
  • Naruo Tokuyasu
    • 1
  • Teruhisa Sakamoto
    • 1
  • Soichiro Honjo
    • 1
  • Hiroaki Saito
    • 1
  • Yoshiyuki Fujiwara
    • 1
  1. 1.Division of Surgical Oncology, Department of Surgery, School of MedicineTottori University Faculty of MedicineYonagoJapan

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