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The maximum dimension of the inferior vena cava is a significant predictor of postoperative mortality in lung cancer patients with idiopathic interstitial pneumonia

  • Mariko Fukui
  • Kazuya Takamochi
  • Kazuhiro Suzuki
  • Akihiro Hotta
  • Katsutoshi Ando
  • Takeshi Matsunaga
  • Shiaki Oh
  • Izumi Kawagoe
  • Kenji SuzukiEmail author
Original Article

Abstract

Purpose

Several vascular measurements in computed tomography (CT) were reported to be indicators of pulmonary hypertension in chronic obstructive pulmonary disease (COPD) patients. We evaluated the usefulness of these parameters as predictors of postoperative mortality in lung cancer patients with IIP.

Methods

This retrospective study was performed on 1888 patients. The following CT findings were evaluated: diameter of the main pulmonary artery, ascending aorta, and the short axis of the inferior vena cava (IVC). Univariate and multivariate analyses were conducted to determine predictors of surgical mortality.

Results

In the IIP patients, the 90-day mortality was 0.8%, and the 2-year mortality was 5.8%. Regarding the 90-day mortality in patients with IIP, a multivariate analysis revealed a short axis of IVC > 21 mm [odds ratio (OR) 6.4, p < 0.01) and the risk score reported by Japanese Association for Chest Surgery (JACS) (OR 1.4, p = 0.01) as independent predictors. Regarding the 2-year mortality in patients with IIP, a multivariate analysis revealed IVC > 21 mm (OR 2.3, p < 0.04), %VC < 80% (OR 2.4, p = 0.02), and pathological cancer stages II and III vs. I (OR 7.2, p < 0.001) as independent predictors.

Conclusions

Enlargement of the IVC as measured by CT was a significant predictor of mortality after surgery for lung cancer with IIP patients.

Keywords

Inferior vena cava Idiopathic interstitial pneumonia Lung cancer Surgical mortality 

Notes

Compliance with ethical standards

Conflict of interest

None declared.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2019

Authors and Affiliations

  • Mariko Fukui
    • 1
  • Kazuya Takamochi
    • 1
  • Kazuhiro Suzuki
    • 2
  • Akihiro Hotta
    • 2
  • Katsutoshi Ando
    • 3
  • Takeshi Matsunaga
    • 1
  • Shiaki Oh
    • 1
  • Izumi Kawagoe
    • 4
  • Kenji Suzuki
    • 1
    Email author
  1. 1.Department of General Thoracic SurgeryJuntendo University School of MedicineTokyoJapan
  2. 2.Department of RadiologyJuntendo University School of MedicineTokyoJapan
  3. 3.Department of Respiratory MedicineJuntendo University School of MedicineTokyoJapan
  4. 4.Department of AnesthesiologyJuntendo University School of MedicineTokyoJapan

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