Surgery Today

, Volume 49, Issue 1, pp 15–20 | Cite as

Colon cancer with perforation

  • Kensuke Otani
  • Kazushige Kawai
  • Keisuke Hata
  • Toshiaki Tanaka
  • Takeshi Nishikawa
  • Kazuhito Sasaki
  • Manabu Kaneko
  • Koji Murono
  • Shigenobu Emoto
  • Hiroaki Nozawa
Review Article


Perforation of the colon is a rare complication for patients with colon cancer and usually requires emergent surgery. The characteristics of perforation differ based on the site of perforation, presenting as either perforation at the cancer site or perforation proximal to the cancer site. Peritonitis due to perforation tends to be more severe in cases of perforation proximal to the cancer site; however, the difference in the outcome between the two types remains unclear. Surgical treatment of colon cancer with perforation has changed over time. Recently, many reports have shown the safety and effectiveness of single-stage operation consisting of resection and primary anastomosis with intraoperative colonic lavage. Under certain conditions, laparoscopic surgery can be feasible and help minimize the invasion. However, emergent surgery for colon cancer with perforation is associated with a high rate of mortality and morbidity. The long-term prognosis seems to have no association with the existence of perforation. Oncologically curative resection may be warranted for perforated colon cancer. In this report, we perform a literature review and investigate the characteristics and surgical strategy for colon cancer with perforation.


Colon cancer Perforation Laparoscopic surgery 


Compliance with ethical standards

Conflict of interest

None of the authors have any conflicts of interest to declare in association with this work.


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Kensuke Otani
    • 1
  • Kazushige Kawai
    • 1
  • Keisuke Hata
    • 1
  • Toshiaki Tanaka
    • 1
  • Takeshi Nishikawa
    • 1
  • Kazuhito Sasaki
    • 1
  • Manabu Kaneko
    • 1
  • Koji Murono
    • 1
  • Shigenobu Emoto
    • 1
  • Hiroaki Nozawa
    • 1
  1. 1.Department of Surgical OncologyThe University of TokyoTokyoJapan

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