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Surgery Today

, Volume 47, Issue 7, pp 795–801 | Cite as

Outcomes of surgery for lung cancer in patients with atrial fibrillation as a preoperative comorbidity: a decade of experience at a single institution in Japan

  • Ryu Kanzaki
  • Toru Kimura
  • Tomohiro Kawamura
  • Soichiro Funaki
  • Yasushi Shintani
  • Masato Minami
  • Meinoshin Okumura
Original Article
  • 266 Downloads

Abstract

Purpose

To investigate the surgical outcomes of surgery for non-small cell lung cancer (NSCLC) in patients with atrial fibrillation (AF) as a preoperative comorbidity.

Methods

Among 805 patients who underwent surgery for NSCLC, 27 (3.4%) had a history of AF. We analyzed the perioperative and long-term outcomes of these 27 patients.

Results

Fourteen patients (52%) had chronic AF and 13 (48%) had paroxysmal AF; being high rates of a comorbid illness. Nineteen patients (70%) underwent lobectomy, and 8 (30%) underwent sublobar resection. Ten patients (37%) received perioperative heparinization. There was no mortality. Other non-AF postoperative complications developed in 8 patients (30%), this incidence being higher than among the patients without AF (16%, 127 out of 778, p = 0.09). A thromboembolic event occurred in one patient (4%). With respect to the long-term outcomes, the 5-year overall survival and disease-free survival rates among the patients with AF were 70.3 and 60.8%, respectively, which were similar to those in the patients without AF (79.8 and 72.6%, p = 0.30 and 0.31).

Conclusions

Lung cancer surgery in patients with AF is safe and provides favorable long-term outcomes; however, thoracic surgeons should monitor these patients carefully for postoperative thromboembolic events.

Keywords

Lung cancer Atrial fibrillation Surgery 

Notes

Compliance with ethical standards

Conflict of interest

We declare no conflicts of interest in association with this study.

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Copyright information

© Springer Japan 2016

Authors and Affiliations

  • Ryu Kanzaki
    • 1
  • Toru Kimura
    • 1
  • Tomohiro Kawamura
    • 1
  • Soichiro Funaki
    • 1
  • Yasushi Shintani
    • 1
  • Masato Minami
    • 1
  • Meinoshin Okumura
    • 1
  1. 1.Department of General Thoracic SurgeryOsaka University Graduate School of MedicineSuitaJapan

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