Surgery Today

, Volume 45, Issue 6, pp 752–758 | Cite as

Clinical outcomes of laparoscopic versus open surgery for primary tumor resection in patients with stage IV colorectal cancer with unresectable metastasis

  • Jong Wan Kim
  • Ji Won Park
  • Sung Chan Park
  • Sun Young Kim
  • Ji Yeon Baek
  • Jae Hwan Oh
Original Article
First Online:
Received:
Accepted:

Abstract

Purpose

The aim of this study was to compare the clinical outcomes of laparoscopic surgery with those of open surgery in patients with colorectal cancer and unresectable metastasis.

Methods

We retrospectively reviewed the medical records of patients who underwent primary tumor resection of colorectal cancer with unresectable metastasis between January 2001 and December 2010.

Results

Of 280 patients, 61 underwent laparoscopic surgery and 219 underwent open surgery. Regarding the short-term outcomes, the amount of blood loss was lower in the laparoscopic group (P = 0.014), although the operation was longer in the laparoscopic group (P = 0.003). The times to flatus (P < 0.001), liquid food intake (P < 0.001), and the duration of hospital stay (P < 0.001) were shorter in the laparoscopic group. The complication rate was lower in the laparoscopic group than in the open group (P = 0.043). Although the overall survival was significantly better in the laparoscopic group in a univariate analysis, there was no significant difference in the overall survival between the two groups in a multivariate analysis (P = 0.482).

Conclusions

Laparoscopic surgery seems to be a safe and feasible option, with short-term benefit for primary tumor resection in patients with stage IV colorectal cancer with unresectable metastasis.

Keywords

Colorectal cancer Laparoscopy Stage IV Metastasis 
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Notes

Acknowledgments

This work was supported by a National Cancer Center Grant (NCC-1210160-2).

Conflict of interest

The authors have no conflicts of interest.

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Copyright information

© Springer Japan 2014

Authors and Affiliations

  • Jong Wan Kim
    • 1
  • Ji Won Park
    • 1
  • Sung Chan Park
    • 1
  • Sun Young Kim
    • 1
  • Ji Yeon Baek
    • 1
  • Jae Hwan Oh
    • 1
  1. 1.Center for Colorectal Cancer, Research Institute and HospitalNational Cancer CenterGoyang-SiRepublic of Korea

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