Surgery Today

, Volume 44, Issue 12, pp 2243–2248 | Cite as

Feasibility of aspirin continuation during the perioperative period for pulmonary resection in lung cancer patients: a retrospective study at a single institute in Japan

  • Ryu Kanzaki
  • Masayoshi Inoue
  • Masato Minami
  • Yasushi Shintani
  • Tomoyuki Nakagiri
  • Soichiro Funaki
  • Noriyoshi Sawabata
  • Meinoshin Okumura
Original Article



To evaluate the feasibility of aspirin continuation during the perioperative period for pulmonary resection in lung cancer patients.


A retrospective study was conducted in 46 patients who were taking aspirin and underwent pulmonary resection. The indications for aspirin were generally a cardiovascular or cerebrovascular comorbidity. Whether to continue or discontinue aspirin was determined based on the severity of the cardiovascular or cerebrovascular comorbidity, along with the patient’s overall condition. The intraoperative and postoperative outcomes were compared between patients continuing and those discontinuing aspirin.


Twenty patients continued (group C) and 26 patients discontinued (group D) aspirin. The length of the operation (226 ± 97 min in group C vs. 189 ± 90 min in group D), intraoperative bleeding (234 ± 232 vs. 204 ± 367 g) and average pleural discharge on postoperative days 1, 2 and 3 (331, 230 and 215 vs. 304, 210 and 174 ml/day) showed no significant differences between the two groups. The postoperative complication rates were also not significantly different between the two groups [eight patients (40 %) in group C vs. nine patients (35 %) in group D].


Continuous administration of aspirin during the perioperative period for pulmonary resection in lung cancer patients appears to be clinically feasible in the Japanese population.


Lung cancer Aspirin Surgery 


Conflict of interest

Ryu Kanzaki and the co-authors have no conflicts of interest to declare.


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Copyright information

© Springer Japan 2014

Authors and Affiliations

  • Ryu Kanzaki
    • 1
  • Masayoshi Inoue
    • 1
  • Masato Minami
    • 1
  • Yasushi Shintani
    • 1
  • Tomoyuki Nakagiri
    • 1
  • Soichiro Funaki
    • 1
  • Noriyoshi Sawabata
    • 1
  • Meinoshin Okumura
    • 1
  1. 1.Department of General Thoracic SurgeryOsaka University Graduate School of MedicineSuitaJapan

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