Incidence and risk factors of surgical site infection in general surgery in a developing country
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To investigate the incidence of surgical site infections (SSIs) according to risk factors, etiological agents, antimicrobial resistance rates of pathogens, and antimicrobial prophylaxis (AMP) in a developing country.
Prospective surveillance of SSIs was carried out in general surgery (GS) units between May 2005 and April 2009.
SSI was diagnosed in 415 (10.8 %) patients. Cefazolin was used as AMP in 780 (49 %) operations, whereas broad-spectrum antibiotics were used in the remaining operations. AMP was administered for >24 h in 69 and 64 % of the GS patients. The most significant risk factors for SSI after GS were total parenteral nutrition, transfusion, and a drainage catheter. The most common pathogen was Escherichia coli, but all the isolated pathogens were multiresistant.
AMP is effective for reducing the risk of SSI; however, the prolonged use of AMP and broad-spectrum antibiotics may be associated with the emergence of resistant bacterial strains.
KeywordsSurgery Antimicrobial prophylaxis Duration Multidrug resistant Infection Acinetobacter spp
We thank the Editing Office of Erciyes University for suggestions about English usage.
Conflict of interest
No competing financial interests exist.
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