Effect of low central venous pressure on postoperative pulmonary complications in patients undergoing liver transplantation
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To investigate the effect of the low central venous pressure (LCVP) technique on postoperative pulmonary complications in patients undergoing liver transplantation.
Sixty-five adult patients were randomly divided into a LCVP group (n = 33) and a control group (n = 32). The CVP was maintained below 5 mmHg or 40 % lower than baseline in the LCVP group, by manipulating the patient’s posture, limiting infusion volume, and administration of nitroglycerine. Recipients in the control group received standard care. The volume of intraoperative blood loss and transfusion, and postoperative pulmonary complications of the two groups were compared.
The LCVP group had a significantly earlier tracheal extubation (33 ± 33 vs. 53 ± 36 h, P < 0.05), and lower rate of postoperative pulmonary complications (42.8 vs. 71.4 %, P < 0.05) in comparison to the control group. The most frequent complication was pleural effusion (28.5 vs. 67.8 %, P < 0.05), followed by pneumonia (24.2 vs. 57.1 %, P < 0.05) and pulmonary edema (3.1 vs. 14.3 %, P < 0.05).
The LCVP technique during liver transplantation could decrease postoperative pulmonary complications.
KeywordsLiver transplantation Low central venous pressure Pulmonary complication Blood loss Transfusion
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