Surgery Today

, Volume 42, Issue 12, pp 1244–1247 | Cite as

Lymphoid hyperplasia detected as a single mass in the gallbladder: report of a case

  • Satoshi Yamamoto
  • Tadashi Tsukamoto
  • Akishige Kanazawa
  • Sadatoshi Shimizu
  • Manabu Mikamori
  • Yushi Fujiwara
  • Hisashi Nagahara
  • Zhang Xiang
  • Katsunobu Sakurai
  • Ken Inoue
Case Report
First Online:
Received:
Accepted:

Abstract

We herein report a case of lymphoid hyperplasia of the gallbladder that showed unique images on computed tomography and ultrasonography. A 42-year-old female was referred to our hospital for evaluation and treatment of a gallbladder tumor. Ultrasonography and computed tomography showed a mass in the wall of the gallbladder neck, without typical findings of benign or malignant tumors. The serum levels of tumor markers, such as carcinoembryonic antigen, carbohydrate antigen 19-9, alpha-fetoprotein, and cytokeratin 19 fragment, were all within normal limits. Laparoscopic cholecystectomy was therefore performed. There were no stones in the gallbladder. Macroscopically, the submural tumor had a clear border without a capsule and a cystic portion. Its cut surface was grayish white. Microscopically, many lymph follicles with germinal centers were recognized in the subserosal layer. The lymphocytes were morphologically normal. We diagnosed lymphoid hyperplasia with chronic cholecystitis. Lymphoid hyperplasia of the gallbladder is extremely rare.

Keywords

Lymphoid hyperplasia Gallbladder Single mass Computed tomography Ultrasonography 
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Notes

Conflict of interest

Satoshi Yamamoto and co-authors have no conflict of interest to declare.

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Copyright information

© Springer 2012

Authors and Affiliations

  • Satoshi Yamamoto
    • 1
    • 2
  • Tadashi Tsukamoto
    • 1
  • Akishige Kanazawa
    • 1
  • Sadatoshi Shimizu
    • 1
  • Manabu Mikamori
    • 1
  • Yushi Fujiwara
    • 1
  • Hisashi Nagahara
    • 1
  • Zhang Xiang
    • 1
  • Katsunobu Sakurai
    • 1
  • Ken Inoue
    • 3
  1. 1.Department of Hepato-Biliary-Pancreatic SurgeryOsaka City General Medical HospitalOsakaJapan
  2. 2.Hepato-Biliary-Pancreatic Surgery Division, Department of SurgeryUniversity of TokyoTokyoJapan
  3. 3.Department of PathologyOsaka City General Medical HospitalOsakaJapan

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