Surgery Today

, Volume 41, Issue 2, pp 210–215 | Cite as

Investigation of the recurrence patterns of gastric cancer following a curative resection

  • Jingyu Deng
  • Han Liang
  • Dianchang Wang
  • Dan Sun
  • Yi Pan
  • Yong Liu
Original Article

Abstract

Purpose

The goal of this study was to investigate the recurrence patterns of gastric cancer and determine the predictive information of recurrence patterns of gastric cancer following a curative resection.

Methods

This study retrospectively analyzed the data of 308 gastric cancer patients who underwent a curative resection, to identify the factors associated with the recurrence patterns.

Results

One hundred and sixty-nine gastric cancer patients had recurrence following curative resection. One hundred and twenty-six patients were observed for 3 years after the operation. Locoregional recurrence formed part of the recurrence pattern in 107 patients, peritoneal dissemination was observed in 98 patients, and distant metastasis occurred in 22 patients. A multivariate analysis revealed that locoregional recurrence was only associated with the Lauren classification (P = 0.003); peritoneal dissemination was only associated with N stage (P < 0.001); and distant metastasis was only associated with the Lauren classification (P = 0.016).

Conclusions

Locoregional recurrence, peritoneal dissemination, and distant metastasis were the most common recurrence patterns of gastric cancer following a curative resection. Each recurrence pattern is associated with specific clinicopathological factors.

Key words

Gastric cancer Disease-free survival Recurrence Multivariate analysis 

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Copyright information

© Springer 2011

Authors and Affiliations

  • Jingyu Deng
    • 1
  • Han Liang
    • 1
  • Dianchang Wang
    • 1
  • Dan Sun
    • 3
  • Yi Pan
    • 2
  • Yong Liu
    • 1
  1. 1.Gastric Cancer Surgery DivisionTianjin Medical University Cancer Hospital and City Key Laboratory of Tianjin Cancer CenterTianjinPR China
  2. 2.Department of PathologyTianjin Medical University Cancer HospitalTianjinPR China
  3. 3.Institute of Lung CancerTianjin Medical University General HospitalTianjinPR China

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