Surgery Today

, Volume 40, Issue 5, pp 440–443 | Cite as

Prognostic nutritional Index: A tool to predict the biological aggressiveness of gastric carcinoma

  • Tadahiro Nozoe
  • Mizuki Ninomiya
  • Takashi Maeda
  • Akito Matsukuma
  • Hideaki Nakashima
  • Takahiro Ezaki
Original Article



The prognostic nutritional index (PNI), which is calculated based on the serum albumin concentration and the peripheral blood lymphocyte count, has been used to assess the immunological and nutritional condition of patients with digestive diseases. However, its value as an indicator of aggressiveness in gastric carcinoma has not been fully investigated.


Two hundred and forty-eight cases of gastric carcinoma were studied with regard to the relationship between the preoperative PNI value and the clinicopathological characteristics of the patients.


A lower preoperative PNI value significantly correlated with greater tumor depth, lymph node metastasis, lymphatic permeation, and venous invasion. Moreover, the PNI value proved to be an independent prognostic indicator in gastric carcinoma.


The PNI value can be a useful tool to predict the prognosis of patients with gastric carcinoma.

Key words

Gastric carcinoma Prognostic nutritional index Prognostic indicator 


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Copyright information

© Springer 2010

Authors and Affiliations

  • Tadahiro Nozoe
    • 1
  • Mizuki Ninomiya
    • 1
  • Takashi Maeda
    • 1
  • Akito Matsukuma
    • 1
  • Hideaki Nakashima
    • 1
  • Takahiro Ezaki
    • 1
  1. 1.Department of SurgeryFukuoka Higashi Medical CenterKogaJapan

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