Surgery Today

, Volume 38, Issue 12, pp 1129–1132 | Cite as

Metastatic liposarcoma in the jejunum causing intussusception: Report of a case

  • Yutaka Shibata
  • Kouhei Sato
  • Masashi Kodama
  • Hiroshi Nanjyo
Case Report

Abstract

We report a case of metastatic liposarcoma in the jejunum manifesting as intestinal intussusception. A 75-year-old man underwent wide excision of a dedifferentiated liposarcoma in his left thigh, followed by adjuvant radiation therapy. He was referred to our department 7 months later with colicky abdominal pain and vomiting. Abdominal radiography showed an intussusception of the small intestine. Laparotomy revealed an antegrade jejunojejunal intussusception, and we resected the jejunum containing the tumor without attempting manual reduction. Histological examination confirmed that the tumor was a metastasis of the liposarcoma. The patient died of pulmonary metastasis 3 months later.

Key words

Liposarcoma Metastasis Jejunum Intussusception 

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References

  1. 1.
    Dei Tos AP. Liposarcoma: new entities and evolving concepts. Ann Diagn Pathol 2000;4:252–266.PubMedCrossRefGoogle Scholar
  2. 2.
    Fletcher CDM, Unni KK, Mertens F: Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC press; 2002. p. 35–46.Google Scholar
  3. 3.
    Huang HY, Brennan MF, Singer S, Antonescu CR. Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation. Mod Pathol 2005;18:976–984.PubMedCrossRefGoogle Scholar
  4. 4.
    Henricks WH, Chu YC, Goldblum JR, Weiss SW. Dedifferentiated liposarcoma. A clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation. Am J Surg Pathol 1997;21:271–2781.PubMedCrossRefGoogle Scholar
  5. 5.
    Singer S, Antonescu CR, Riedel E, Brennan MF. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg 2003;238:358–370.PubMedGoogle Scholar
  6. 6.
    Hasegawa T, Seki K, Hasegawa F, Matsuno Y, Shimoda T, Hirose T, et al. Dedifferentiated liposarcoma of retroperitoneum and mesentery: varied growth patterns and histological grades—a clinicopathologic study of 32 cases. Hum Pathol 2000;31:717–727.PubMedCrossRefGoogle Scholar
  7. 7.
    McCormick D, Mentzel T, Beharm A, Fletcher CDM. Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognosis subgroup among pleomorphic sarcomas. Am J Surg Pathol 1994;18:1213–1223.PubMedCrossRefGoogle Scholar
  8. 8.
    Monjazeb A, Stanton C, Levine EA. Intussusception secondary to metastasis from a low-grade retroperitoneal liposarcoma. Am Surg 2004;70:775–778.PubMedGoogle Scholar
  9. 9.
    Wolfhagen FH, Mensing JW, Veen HF, Dees A. Late recurrence of liposarcoma simulating adenoma of the duodenum. Neth J Med 1999;54:231–234.PubMedCrossRefGoogle Scholar
  10. 10.
    Liaw CC, Wang CS, Ng KK, Lin PY. Enteric intussusception due to metastatic intestinal tumors. J Formos Med Assoc 1997;96:125–128.PubMedGoogle Scholar
  11. 11.
    Nagawa H, Tsuno N, Saito H, Muto T. Ileal obstruction due to metastatic liposarcoma: a case report. Gastroenterol Jpn 1993;28:706–711.PubMedGoogle Scholar
  12. 12.
    Weiss SW, Rao VK. Well-differentiated liposarcoma (atypical lipoma) of deep soft tissue of the extremities, retroperitoneum, and miscellaneous sites. A follow-up study of 92 cases with analysis of the incidence of “dedifferentiation”. Am J Surg Pathol 1992;16:1051–1058.PubMedCrossRefGoogle Scholar
  13. 13.
    Strander H, Turesson I, Cavallin-Stahl E. A systematic overview of radiation therapy effects in soft tissue sarcomas. Acta Oncol 2003;42:516–531.PubMedCrossRefGoogle Scholar
  14. 14.
    Jones RL, Fisher C, Al-Muderis O, Judson IR. Differential sensitivity of liposarcoma subtypes to chemotherapy. Eur J Cancer 2005;41:2853–2856.PubMedCrossRefGoogle Scholar
  15. 15.
    Haas EM, Etter EL, Ellis S, Taylor TV. Adult intussusception. Am J Surg 2003;186:75–76.PubMedCrossRefGoogle Scholar
  16. 16.
    Azar T, Berger DL. Adult intussusception. Ann Surg 1997;226:134–138.PubMedCrossRefGoogle Scholar

Copyright information

© Springer 2008

Authors and Affiliations

  • Yutaka Shibata
    • 1
  • Kouhei Sato
    • 1
  • Masashi Kodama
    • 1
  • Hiroshi Nanjyo
    • 2
  1. 1.Department of SurgeryKotou General HospitalAkitaJapan
  2. 2.Division of Clinical PathologyAkita University School of MedicineAkitaJapan

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