Surgery Today

, Volume 37, Issue 1, pp 34–37 | Cite as

Needle Track Dissemination of Follicular Thyroid Carcinoma Following Fine-Needle Aspiration Biopsy: Report of a Case

  • Naotaka Uchida
  • Takako Suda
  • Tomoko Inoue
  • Yoshikazu Fujiwara
  • Kiyosuke Ishiguro


Few reports have been concerned with the risk of needle track dissemination of tumor cells following fine-needle aspiration biopsy, especially for follicular thyroid nodules. A 61-year-old woman who underwent fine-needle aspiration biopsy and surgery 5 years previously for follicular thyroid adenoma presented with nodules that had developed in the sternocleidomastoid and omohyoid muscles of the anterior neck. These nodules were located along a line from the skin to the thyroid that coincided with the needle track of the previous biopsy. Following surgical resection, histological diagnosis determined the nodules to be follicular carcinoma. The clinical course and linear arrangement of the lesions were highly suggestive of needle track dissemination of tumor cells following fine-needle aspiration biopsy. Although fine-needle aspiration biopsy is a useful tool for the diagnosis of thyroid nodules, it is important to consider the risk of tumor cell dissemination.

Key words

Follicular thyroid carcinoma Fine-needle aspiration biopsy Needle track dissemination 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Hundhal, SA, Fleming, ID, Fremgen, AM, Menck, HR 1998A National Cancer Data Base report on 53.856 cases of thyroid carcinoma treated in the U.S., 1985–1995 (see comments)Cancer8324346CrossRefGoogle Scholar
  2. 2.
    Morgan, JL, Serpell, JW, Cheng, MS 2003Fine-needle aspiration cytology of thyroid nodules: how useful is it?Aust N Z J Surg734803CrossRefGoogle Scholar
  3. 3.
    Agrawal, S 1995Diagnostic accuracy and role of fine needle aspiration cytology in management of thyroid nodulesJ Surg Oncol5816872PubMedGoogle Scholar
  4. 4.
    Mazzaferri, EL 1993Management of a solitary thyroid noduleN Engl J Med3285539PubMedCrossRefGoogle Scholar
  5. 5.
    Haigh, PI 2002Follicular thyroid carcinomaCurr Treat Options Oncol334954PubMedGoogle Scholar
  6. 6.
    Stolier, A, Skinner, J, Levine, EA 2000A prospective study of seeding of the skin after core biopsy of the breastAm J Surg1801047PubMedCrossRefGoogle Scholar
  7. 7.
    Thurfjell, MG, Jansson, T, Nordgren, H, Bergh, J, Lindgren, A, Thurfjell, E 2000Local breast cancer recurrence caused by mammographically guided punctureActa Radiol4143540PubMedCrossRefGoogle Scholar
  8. 8.
    Smith, EH 1991Complications of percutaneous abdominal fine needle biopsy: reviewRadiology1782538PubMedGoogle Scholar
  9. 9.
    Atkinson, BF 1993Fine needle aspiration of the thyroidMonogr Pathol3516699PubMedGoogle Scholar
  10. 10.
    Karwowski, JK, Nowels, KW, McDougall, IR, Weigel, RJ 2002Needle track seeding of papillary thyroid carcinoma from fine needle aspiration biopsy. A case reportActa Cytol465915PubMedGoogle Scholar
  11. 11.
    Hales, SM, Hsu, SF 1990Needle tract implantation of papillary carcinoma of the thyroid following aspiration biopsyActa Cytol348014PubMedGoogle Scholar
  12. 12.
    Panunzi, C, Paliotta, DS, Papini, E, Petrucci, L, Rinaldi, R, Nardi, F 1994Cutaneous seeding of a follicular thyroid cancer after fine-needle aspirationDiagn Cytopathol101568PubMedGoogle Scholar
  13. 13.
    Thompson, LD, Wieneke, JA, Paal, E, Frommelt, RA, Adair, CF, Heffess, CS 2001A clinicopathologic study of minimally invasive follicular carcinoma of the thyroid gland with a review of the English literatureCancer9150524PubMedCrossRefGoogle Scholar
  14. 14.
    Guidelines of the Papanicolaou Society of Cytopathology for the Examination of Fine-Needle Aspiration Specimens from Thyroid Nodules1996The Papanicolaou Society of Cytopathology Task Force on Standards of PracticeMod Pathol97105Google Scholar
  15. 15.
    Ito, Y, Tomoda, C, Uruno, T, Takamura, Y, Miya, A, Kobayasji, K,  et al. 2005Needle tract implantation of papillary thyroid carcinoma after fine-needle aspiration biopsyWorld J Surg2915449PubMedCrossRefGoogle Scholar
  16. 16.
    Mighell, AJ, High, AS 1998Histological identification of carcinoma in 21 gauge needle tracks after fine needle aspiration biopsy of head and neck carcinomaJ Clin Pathol5124152PubMedCrossRefGoogle Scholar
  17. 17.
    Papini, E, Petrucci, L, Guglielmi, R, Panunzi, C, Rinaldi, R, Bacci, V,  et al. 1998Long-term changes in nodular goiter: a 5-year prospective randomized trial of levothyroxine suppressive therapy for benign cold thyroid nodulesJ Clin Endocrinol Metab837803PubMedCrossRefGoogle Scholar
  18. 18.
    Fogelfeld, L, Wiviott, MB, Shore-Freedman, E, Blend, M, Bekerman, C, Pinsky, S,  et al. 1989Recurrence of thyroid nodules after surgical removal in patients irradiated in childhood for benign conditionsN Engl J Med32083540PubMedCrossRefGoogle Scholar
  19. 19.
    Ross, DS 1994Hyperthyroidism, thyroid hormone therapy, and boneThyroid431926PubMedGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 2007

Authors and Affiliations

  • Naotaka Uchida
    • 1
  • Takako Suda
    • 1
  • Tomoko Inoue
    • 1
  • Yoshikazu Fujiwara
    • 1
  • Kiyosuke Ishiguro
    • 1
  1. 1.Division of Organ Regeneration Surgery, Department of Surgery, Faculty of MedicineTottori UniversityTottoriJapan

Personalised recommendations