Primary Rhabdomyosarcoma of the Breast in a 13-Year-Old Girl: Report of a Case
- First Online:
- 98 Downloads
We report a case of primary alveolar rhabdomyosarcoma of the breast in a 13-year-old Japanese girl. The patient initially presented with a 13 × 8-cm mass in her left breast, which was diagnosed as alveolar rhabdomyosarcoma after an excisional biopsy. Genetic expression of the tumor revealed t(2;13)(q35–37;q14). She underwent modified radical mastectomy (Bt + Ax) and nine lymph nodes were found to be involved. Systemic examinations showed multiple bone and lung metastases 2 weeks after her operation. Despite chemotherapy with doxorubicin, ifosfamide, and actinomycin D, which resulted in remission for 6 months, she died of the disease 8 months after surgery.
Key wordsRhabdomyosarcoma Breast Girl
Unable to display preview. Download preview PDF.
- 1.Crist, WM, Garnsey, L, Beltangady, MS, Gehan, E, Ruymann, F, Webber, B, et al. 1990Prognosis in children with rhabdomyosarcoma: a report of the Intergroup rhabdomyosarcoma studies I and II. Intergroup Rhabdomyosarcoma CommitteeJ Clin Oncol817689Google Scholar
- 4.Raney, RB, Anderson, JR, Barr, FG, Donaldson, SS, Pappo, AS, Qualman, SJ, et al. 2001Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of intergroup rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study VJ Pediatr Hematol Oncol2321520PubMedCrossRefGoogle Scholar