Surgery Today

, Volume 36, Issue 10, pp 934–936

Granular Cell Tumor as an Unusual Cause of Obstruction at the Hepatic Hilum: Report of a Case

  • Rajiv Lochan
  • Shlokarth Balupuri
  • Mark K. Bennett
  • Derek M. Manas


A diagnosis of malignancy is reasonably assumed when a lesion is found at the hilum or bile ducts in a patient with jaundice who has never undergone biliary surgery. Although benign tumors occasionally develop in this location, preoperative recognition is difficult and most are treated as malignant lesions. We illustrate this clinical scenario in this case report of a granular cell tumor (GCT) that developed at the biliary bifurcation, necessitating right hemi-hepatectomy with extrahepatic biliary tree excision. We describe the clinical presentation, imaging findings, treatment, and histological findings of this tumor. Although rare, a GCT can develop at the hilum and mimic a malignant lesion such as cholangiocarcinoma (CC) radiologically. To our knowledge, this is the fourth report of a GCT at the hilum of the liver. However, the possibility of this tumor should be considered in the differential diagnosis of a lesion in this location.

Key words

Hilar tumor Benign hilar mass Granular cell tumor 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Gerhards, MF, Vos, P, van Gulik, TM, Rauws, EA, Bosma, A, Gouma, DJ 2001Incidence of benign lesions in patients resected for suspicious hilar obstructionBr J Surg884851PubMedCrossRefGoogle Scholar
  2. 2.
    Neumann, V, Li, RD, Rosenthal, NS, Burrell, M, Ball, TJ 1976Adenocarcinoma in biliary papillomatosisGastroenterology70779PubMedGoogle Scholar
  3. 3.
    Cook, DJ, S, B, Vincic, LH 1988Adenomyoma of the CBDAm J Gastroenterol83432PubMedGoogle Scholar
  4. 4.
    te Boekhorst, DS, Gerhards, MF, van Gulik, TM, Gouma, DJ 2000Granular cell tumor at the hepatic duct confluence mimicking Klatskin tumor: a report of two cases and a review of the literatureDig Surg17299303PubMedCrossRefGoogle Scholar
  5. 5.
    Heuer, T, Lahrtz, HJ, Gerards, H, Berkovic, D, Kania, U, Reis, HE 2004Posthepatic icterus caused by a solitary granular cell tumor of the common bile ductZ Gastroenterol423235PubMedCrossRefGoogle Scholar
  6. 6.
    Abrikosoff, A 1926Uber myome ausgehend von der quergestreiften willkurlichen muskulaturVirchows Arch26021533CrossRefGoogle Scholar
  7. 7.
    Coggins, R 1952Granular cell myoblastoma of the common bile ductArch Pathol54398402Google Scholar
  8. 8.
    Klima, M, Peters, J 1987Malignant granular cell tumourArch Pathol Lab Med1111703Google Scholar
  9. 9.
    Andersson, R, Andren-Sandberg, A, Lundstedt, C, Tranberg, K 1996Implantation metastases from gastrointestinal cancer after percutaneous puncture or biliary drainageEur J Surg1625514PubMedGoogle Scholar
  10. 10.
    D'Angelica, MI, Jarnagin, WR, Blumgart, LH 2004Resectable hilar cholangiocarcinoma: surgical treatment and long-term outcomeSurg Today3488590PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Tokyo 2006

Authors and Affiliations

  • Rajiv Lochan
    • 1
  • Shlokarth Balupuri
    • 1
  • Mark K. Bennett
    • 1
  • Derek M. Manas
    • 1
  1. 1.Department of Hepato-Pancreato-Biliary and Transplant Surgery, Level 4 GI Secretaries OfficeFreeman HospitalNewcastle upon TyneUK

Personalised recommendations