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Acta Diabetologica

, Volume 55, Issue 10, pp 1059–1066 | Cite as

Real-world use of self-monitoring of blood glucose in people with type 2 diabetes: an urgent need for improvement

  • Maria Chiara RossiEmail author
  • Giuseppe Lucisano
  • Antonio Ceriello
  • Chiara Mazzucchelli
  • Nicoletta Musacchio
  • Alessandro Ozzello
  • Antonio Nicolucci
  • Paolo Di Bartolo
  • the AMD Annals-SMBG Study Group
Original Article

Abstract

Aims

To assess use of self-monitoring of blood glucose (SMBG) in type 2 diabetes (T2DM) in the context of a continuous quality improvement initiative (AMD Annals).

Methods

14 quality-of-care indicators were developed, including frequency of SMBG, fasting blood glucose (FBG), and post-prandial glucose (PPG) levels, and hypoglycemia and hyperglycemia episodes. Clinical data and SMBG values downloaded from any glucose meter were obtained from electronic medical records. The most frequently used glucose-lowering treatment regimens were identified and the indicators were assessed separately by regimen.

Results

Overall, 21 Italian centers and 13,331 patients (accounting for 35,657 HbA1c tests and 8.44 million SMBG values collected during 2014 and 2015) were included in the analysis; 11 therapeutic regimens were selected. Patients in regimens not including insulin performed 15–23 measurements per patient-month, those treated with basal insulin 32.1 tests/patient-month, and those treated with basal and short-acting insulin 53–58 tests/patient-month. In all treatment regimens, PPG measurements represented a minority of all tests; pre-breakfast measurements accounted for about 50% of all FBG values. Mean FBG levels exceeded 130 mg/dl in 49.3–88.3% of the cases in the different treatment regimens, while PPG levels were over 140 mg/dl in 46.7–81.0%. From 5.7 to 32.7%, patients in the different regimens had at least one episode of hypoglycemia (< 70 mg/dl), while from 3.7 to 47.7% had at least one episode of hyperglycemia (> 300 mg/dl).

Conclusions

SMBG is underutilized in patients with T2DM treated or not with insulin. In all treatment groups, PPG is seldom investigated. Poor metabolic control and rates of hyper- and hypoglycemia deserve consideration in all treatment groups.

Keywords

Self-monitoring blood glucose Type 2 diabetes Quality of care Benchmarking Adherence 

Abbreviations

ACARB

Acarbose

ADA

American Diabetes Association

AMD

Associazione Medici Diabetologi

BASAL

Basal insulin

DPP4

Dipeptidyl peptidase-4 inhibitor

EASD

European Association for the Study of Diabetes

EMR

Electronic medical record

FBG

Fasting blood glucose

GLP1-RAS

Glucagon-like peptide-1 receptor agonists

HBA1C

Glycated hemoglobin

IDF

International Diabetes Federation

METF

Metformin

OHA

Oral hypoglycemic agent

PPG

Post-prandial glucose

SD

Standard deviation

SG

Secretagogue

SHORT

Short-acting insulin

SMBG

Self-monitoring blood glucose

T2DM

Type 2 diabetes

95% CI

95% confidence interval

Notes

Acknowledgements

The study was promoted by the AMD scientific society through an unconditional Grant by Sanofi SpA, Milan, Italy. The authors thank the participating diabetes outpatient centers for their contribution. The authors acknowledge Sanofi—Italy for having supported this work. The sponsor did not participate in the design or conduct of this study; in the collection, management, analysis, or interpretation of data; in the writing of the manuscript; and in the preparation, review, approval, or decision to submit this manuscript for publication. AMD ANNALS-SMBG Study Group list of investigators: Nuzzi Annamaria—Alba, Canale (CN), Velussi Mario—Aurisina (TS), Spanu Francesca—Cagliari, Del Buono Andrea—Cellole (CE), Santantonio Graziano—Civitavecchia (RM), Magro Giampaolo—Cuneo, Garrapa Gabriella—Fano (PU), Antenucci Daniela—Lanciano (CH), Laudato Mario—Maddaloni (CE), Saitta Giovanni—Messina, Stroppiana Mauro—Nizza Monferrato (AT), D’Agati Francesco—Palermo, Anichini Roberto—Pescia (PT), Di Bartolo Paolo—Ravenna, Rastelli Emilio—Riccione (RN), Leotta Sergio—Roma, Felace Giuseppe—Spilimbergo (PN), Lalli Carlo—Spoleto (PG), Tonutti Laura—Udine.

Funding

The study was supported by a unconditional Grant from Sanofi SpA, Milan, Italy.

Compliance with ethical standards

Conflict of interest

The author(s) declare that they have no competing interests.

Statement of human and animal rights

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 (5).

Statement of informed consent

Based on the study design and Italian regulations, the study protocol was approved by the local Ethics Committees and the signed informed consent was not required.

Supplementary material

592_2018_1186_MOESM1_ESM.docx (18 kb)
Supplementary material 1 (DOCX 17 KB)

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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  • Maria Chiara Rossi
    • 1
    Email author
  • Giuseppe Lucisano
    • 1
  • Antonio Ceriello
    • 2
    • 3
  • Chiara Mazzucchelli
    • 4
  • Nicoletta Musacchio
    • 5
  • Alessandro Ozzello
    • 6
  • Antonio Nicolucci
    • 1
  • Paolo Di Bartolo
    • 7
  • the AMD Annals-SMBG Study Group
  1. 1.CORESEARCH - Center for Outcomes Research and Clinical EpidemiologyPescaraItaly
  2. 2.Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomedica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM)BarcelonaSpain
  3. 3.Department of Cardiovascular and Metabolic DiseasesIRCCS MultimedicaSesto San GiovanniItaly
  4. 4.IRCCS San MartinoGenoaItaly
  5. 5.AMDRomeItaly
  6. 6.Asl Torino 3PineroloItaly
  7. 7.AUSL RomagnaRavennaItaly

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