Acta Diabetologica

, Volume 54, Issue 7, pp 703–706 | Cite as

Ultra-marathon 100 km in an islet-transplanted runner

  • Roberto Codella
  • Michela Adamo
  • Paola Maffi
  • Lorenzo Piemonti
  • Antonio Secchi
  • Livio Luzi
Case Report

Keywords

Islet transplantation Ultra-marathon 

Abbreviations

AIR

Acute insulin response

CGM

Continuous glucose monitoring

GAD

Glutamic acid decarboxylase

HbA1c

Glycosylated hemoglobin

HR

Heart rate

IA2

Tyrosine phosphatase-related islet antigen 2

IT

Islet transplantation

LMR

Lymphocyte-to-monocyte ratio

NLR

Neutrophil-to-lymphocyte ratio

PLR

Platelet-to-lymphocyte ratio

T1D

Type 1 diabetes mellitus

ZnT8

Zinc transporter 8

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Ethical standard

All the performed procedures were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Human and animal rights

This article does not contain any study with animals performed by any of the authors.

Informed consent

Informed consent was obtained from the participant included in the study.

References

  1. 1.
    Codella R, Luzi L, Inverardi L, Ricordi C (2015) The anti-inflammatory effects of exercise in the syndromic thread of diabetes and autoimmunity. Eur Rev Med Pharmacol Sci 19:3709–3722PubMedGoogle Scholar
  2. 2.
    Hering BJ, Clarke WR, Bridges ND et al (2016) Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia. Diabetes Care 39:1230–1240. doi: 10.2337/dc15-1988 CrossRefPubMedGoogle Scholar
  3. 3.
    Cryer PE (2010) Hypoglycemia in type 1 diabetes mellitus. Endocrinol Metab Clin North Am 39:641–654. doi: 10.1016/j.ecl.2010.05.003 CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Pellegrini S, Cantarelli E, Sordi V et al (2016) The state of the art of islet transplantation and cell therapy in type 1 diabetes. Acta Diabetol 53:683–691. doi: 10.1007/s00592-016-0847-z CrossRefPubMedGoogle Scholar
  5. 5.
    Surgit O, Ersoz G, Gursel Y, Ersoz S (2001) Effects of exercise training on specific immune parameters in transplant recipients. Transpl Proc 33:3298CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Italia 2016

Authors and Affiliations

  1. 1.Department of Biomedical Sciences for HealthIRCCS Policlinico San Donato, Università degli Studi di MilanoSan Donato Milanese, MilanItaly
  2. 2.Metabolism Research CenterIRCCS Policlinico San DonatoSan Donato MilaneseItaly
  3. 3.Department of Internal Medicine, Transplant Medicine UnitSan Raffaele Scientific InstituteMilanItaly
  4. 4.Diabetes Research Institute (Sr-DRI), San Raffaele Scientific InstituteMilanItaly

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