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Acta Diabetologica

, Volume 48, Issue 4, pp 275–282 | Cite as

Sugar-sweetened and diet beverage consumption is associated with cardiovascular risk factor profile in youth with type 1 diabetes

  • Andrey V. Bortsov
  • Angela D. LieseEmail author
  • Ronny A. Bell
  • Dana Dabelea
  • Ralph B. D’AgostinoJr
  • Richard F. Hamman
  • Georgeanna J. Klingensmith
  • Jean M. Lawrence
  • David M. Maahs
  • Robert McKeown
  • Santica M. Marcovina
  • Joan Thomas
  • Desmond E. Williams
  • Elizabeth J. Mayer-Davis
Original Article

Abstract

The prevalence of cardiovascular disease (CVD) risk factors among youth with type 1 diabetes is high and associated with age, gender, and race/ethnicity. It has also been shown that youth with type 1 diabetes often do not follow dietary recommendations. The objective of this cross-sectional observational study was to explore the association of sugar-sweetened and diet beverage intake with A1c, plasma lipids, adiponectin, leptin, systolic, and diastolic blood pressure in youth with type 1 diabetes. We examined data from 1,806 youth age 10–22 years with type 1 diabetes, of which 22% were minority (10% Hispanic, 8% African Americans, 4% other races) and 48% were female. Sugar-sweetened beverage, diet beverage, and mineral water intake was assessed with a food frequency questionnaire. After adjustment for socio-demographic and clinical covariates, physical activity and total energy intake, high sugar-sweetened beverage intake (at least one serving per day vs. none), was associated with higher levels of total cholesterol, LDL cholesterol, and plasma triglycerides, but not with A1c. High diet beverage intake was associated with higher A1c, total cholesterol, LDL cholesterol, and triglycerides. These associations were partially confounded by body mass index, saturated fat and total fiber intake. High sugar-sweetened beverage intake may have an adverse effect on CVD risk in youth with type 1 diabetes. Diet beverage intake may be a marker of unhealthy lifestyle which, in turn, is associated with worse metabolic control and CVD risk profile in these youth. Youth with diabetes should be encouraged to minimize sugar-sweetened beverage intake.

Keywords

Diabetes mellitus Child Adolescent Beverages Lipids 

Notes

Acknowledgments

Grant Support: SEARCH for Diabetes in Youth is funded by the Centers for Disease Control and Prevention (PA number 00097 and DP-05-069) and supported by the National Institute of Diabetes and Digestive and Kidney Diseases. Site Contract Numbers: Kaiser Permanente Southern California (U01 DP000246), University of Colorado Health Sciences Center (U01 DP000247), Pacific Health Research Institute (U01 DP000245), Children’s Hospital Medical Center (Cincinnati) (U01 DP000248), University of North Carolina at Chapel Hill (U01 DP000254), University of Washington School of Medicine (U01 DP000244), Wake Forest University School of Medicine (U01 DP000250). The contents of this paper are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention and the National Institute of Diabetes and Digestive and Kidney Diseases. The SEARCH for Diabetes in Youth Study is indebted to the many youth and their families, and their health care providers, whose participation made this study possible. The authors wish to acknowledge the involvement of General Clinical Research Centers (GCRC) at the following institutions in the SEARCH for Diabetes in Youth Study: Medical University of South Carolina (Grant number M01 RR01070); Cincinnati Children’s Hospital (Grant number M01 RR08084); Children’s Hospital and Regional Medical Center and the University of Washington School of Medicine (Grant numbers M01RR00037 and M01RR001271); Colorado Pediatric General Clinical Research Center (Grant number M01 RR00069).

References

  1. 1.
    Gidding SS, Dennison BA, Birch LL, Daniels SR, Gilman MW, Lichtenstein AH, Rattay KT, Steinberger J, Stettler N, Van HL (2005) Dietary recommendations for children and adolescents: a guide for practitioners: consensus statement from the American Heart Association. Circulation 112(13):2061–2075PubMedCrossRefGoogle Scholar
  2. 2.
    Berkey CS, Rockett HR, Field AE, Gillman MW, Colditz GA (2004) Sugar-added beverages and adolescent weight change. Obes Res 12(5):778–788PubMedCrossRefGoogle Scholar
  3. 3.
    Phillips SM, Bandini LG, Naumova EN, Cyr H, Colclough S, Dietz WH, Must A (2004) Energy-dense snack food intake in adolescence: longitudinal relationship to weight and fatness. Obes Res 12(3):461–472PubMedCrossRefGoogle Scholar
  4. 4.
    Ludwig DS, Peterson KE, Gortmaker SL (2001) Relation between consumption of sugar-sweetened drinks and childhood obesity: a prospective, observational analysis. Lancet 357(9255):505–508PubMedCrossRefGoogle Scholar
  5. 5.
    Dhingra R, Sullivan L, Jacques PF, Wang TJ, Fox CS, Meigs JB, D’Agostino RB, Gaziano JM, Vasan RS (2007) Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation 116(5):480–488. doi: CIRCULATIONAHA.107.689935 PubMedCrossRefGoogle Scholar
  6. 6.
    Lutsey PL, Steffen LM, Stevens J (2008) Dietary intake and the development of the metabolic syndrome: the atherosclerosis risk in communities study. Circulation 117(6):754–761. doi: CIRCULATIONAHA.107.716159 PubMedCrossRefGoogle Scholar
  7. 7.
    Swarbrick MM, Stanhope KL, Elliott SS, Graham JL, Krauss RM, Christiansen MP, Griffen SC, Keim NL, Havel PJ (2008) Consumption of fructose-sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein-B concentrations in overweight and obese women. Br J Nutr 100(5):947–952. doi: S0007114508968252 PubMedCrossRefGoogle Scholar
  8. 8.
    Rodriguez BL (2006) Dietary studies in the multi-Ethnic Hawaiian population. J Am Diet Assoc 106(2):209–210PubMedCrossRefGoogle Scholar
  9. 9.
    Salem M, Moneir I, Adly AM, Esmat K (2010) Study of coronary artery calcification risk in Egyptian adolescents with type-1 diabetes. Acta Diabetologica. doi: 10.1007/s00592-010-0214-4
  10. 10.
    Mayer-Davis EJ, Nichols M, Liese AD, Bell RA, Dabelea DM, Johansen JM, Pihoker C, Rodriguez BL, Thomas J, Williams D (2006) Dietary intake among youth with diabetes: the SEARCH for Diabetes in Youth Study. J Am Diet Assoc 106(5):689–697PubMedCrossRefGoogle Scholar
  11. 11.
    Overby NC, Margeirsdottir HD, Brunborg C, Andersen LF, Dahl-Jorgensen K (2007) The influence of dietary intake and meal pattern on blood glucose control in children and adolescents using intensive insulin treatment. Diabetologia 50(10):2044–2051. doi: 10.1007/s00125-007-0775-0 PubMedCrossRefGoogle Scholar
  12. 12.
    Group SS (2004) SEARCH for diabetes in youth: a multicenter study of the prevalence, incidence and classification of diabetes mellitus in youth. Control Clin Trials 25(5):458–471CrossRefGoogle Scholar
  13. 13.
    Grieco EM, Cassidy RC (2001) Overview of race and hispanic origin: census 2000 Brief. US Census Bureau, Washington, DCGoogle Scholar
  14. 14.
    Ingram DD, Parker JD, Schenker N, Weed JA, Hamilton B, Arias E, Madans JH (2003) United States Census 2000 population with bridged race categories. Vital Health Stat 2 135:1–55Google Scholar
  15. 15.
    Krowchuk DP, Kreiter SR, Woods CR, Sinal SH, DuRant RH (1998) Problem dieting behaviors among young adolescents. Arch Pediatr Adolesc Med 152(9):884–888PubMedGoogle Scholar
  16. 16.
    Eisenmann JC, Bartee RT, Wang MQ (2002) Physical activity, TV viewing, and weight in US youth: 1999 youth risk behavior survey. Obesity 10(5):379–385CrossRefGoogle Scholar
  17. 17.
    Kuczmarski RJ, Ogden CL, Guo SS, Grummer-Strawn LM, Flegal KM, Mei Z, Wei R, Curtin LR, Roche AF, Johnson CL (2002) 2000 CDC growth charts for the United States: methods and development. Vital Health Stat 11 246:1–190Google Scholar
  18. 18.
    Hainline A Jr, Miller DT, Mather A (1983) The coronary drug project. Role and methods of the Central Laboratory. Control Clin Trials 4(4):377PubMedCrossRefGoogle Scholar
  19. 19.
    Diez JJ, Iglesias P, Fernandez-Reyes MJ, Aguilera A, Bajo MA, varez-Fidalgo P, Codoceo R, Selgas R (2005) Serum concentrations of leptin, adiponectin and resistin, and their relationship with cardiovascular disease in patients with end-stage renal disease. Clin Endocrinol 62(2):242–249CrossRefGoogle Scholar
  20. 20.
    Kleinbaum DG, Kupper LL, Muller KE (1988) Applied regression analysis and other multivariable methods. PWS Publishing Co, USAGoogle Scholar
  21. 21.
    Malik VS, Schulze MB, Hu FB (2006) Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr 84(2):274–288. doi: 84/2/274 PubMedGoogle Scholar
  22. 22.
    Abdulrhman M, El-Hefnawy M, Hussein R, El-Goud AA (2009) The glycemic and peak incremental indices of honey, sucrose and glucose in patients with type 1 diabetes mellitus: effects on C-peptide level-a pilot study. Acta Diabetologica. doi: 10.1007/s00592-009-0167-7
  23. 23.
    Lombardo YB, Drago S, Chicco A, Fainstein-Day P, Gutman R, Gagliardino JJ, Gomez Dumm CL (1996) Long-term administration of a sucrose-rich diet to normal rats: relationship between metabolic and hormonal profiles and morphological changes in the endocrine pancreas. Metabolism 45(12):1527–1532PubMedCrossRefGoogle Scholar
  24. 24.
    Appel LJ, Brands MW, Daniels SR, Karanja N, Elmer PJ, Sacks FM (2006) Dietary approaches to prevent and treat hypertension: a scientific statement from the American Heart Association. Hypertension 47(2):296–308PubMedCrossRefGoogle Scholar
  25. 25.
    Erkkila AT, Sarkkinen ES, Lindi V, Lehto S, Laakso M, Uusitupa MI (2001) APOE polymorphism and the hypertriglyceridemic effect of dietary sucrose. Am J Clin Nutr 73(4):746–752PubMedGoogle Scholar
  26. 26.
    Nadas J, Putz Z, Fovenyi J, Gaal Z, Gyimesi A, Hidvegi T, Hosszufalusi N, Neuwirth G, Oroszlan T, Panczel P, Vandorfi G, Winkler G, Wittmann I, Jermendy G (2009) Cardiometabolic risk and educational level in adult patients with type 1 diabetes. Acta Diabetol 46(2):159–162PubMedCrossRefGoogle Scholar
  27. 27.
    Willett WC (1998) Nutritional Epidemiology, 2nd edn. Oxford University Press, OxfordGoogle Scholar
  28. 28.
    Tarquini R, Lazzeri C, Pala L, Rotella CM, Gensini GF (2010) The diabetic cardiomyopathy. Acta Diabetologica. doi: 10.1007/s00592-010-0180-x

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Andrey V. Bortsov
    • 1
  • Angela D. Liese
    • 1
    • 2
    Email author
  • Ronny A. Bell
    • 3
  • Dana Dabelea
    • 4
  • Ralph B. D’AgostinoJr
    • 5
  • Richard F. Hamman
    • 4
  • Georgeanna J. Klingensmith
    • 4
    • 6
  • Jean M. Lawrence
    • 7
  • David M. Maahs
    • 4
    • 6
  • Robert McKeown
    • 1
  • Santica M. Marcovina
    • 8
  • Joan Thomas
    • 10
  • Desmond E. Williams
    • 9
  • Elizabeth J. Mayer-Davis
    • 1
    • 10
  1. 1.Department of Epidemiology and Biostatistics, Arnold School of Public HealthUniversity of South CarolinaColumbiaUSA
  2. 2.Center for Research in Nutrition and Health Disparities, Arnold School of Public HealthUniversity of South CarolinaColumbiaUSA
  3. 3.Department of Epidemiology and PreventionWake Forest University School of MedicineWinston-SalemUSA
  4. 4.University of Colorado Health Sciences CenterDenverUSA
  5. 5.Department of Biostatistical SciencesWake Forest University School of MedicineWinston-SalemUSA
  6. 6.University of Colorado Barbara Davis CenterDenverUSA
  7. 7.Department of Research and EvaluationKaiser Permanente Southern CaliforniaPasadenaUSA
  8. 8.Northwest Lipid Research Laboratories, Department of MedicineUniversity of WashingtonSeattleUSA
  9. 9.Division of Diabetes TranslationCenters for Disease Control and Prevention/NCCDPHPAtlantaUSA
  10. 10.Department of NutritionUniversity of North CarolinaChapel HillUSA

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