Complications of spine surgery for metastasis

  • Vasilios G. Igoumenou
  • Andreas F. MavrogenisEmail author
  • Andrea Angelini
  • Riccardo Baracco
  • Ahmed Benzakour
  • Thami Benzakour
  • Martin Bork
  • Farzam Vazifehdan
  • Ugo Nena
  • Pietro Ruggieri
General Review • SPINE - METASTASES


The spinal column represents the third most common site for metastases after the lungs and the liver, and the most common site for metastatic bone disease. With life-extending advances in the systemic treatment of cancer patients, the surgical procedures performed for spinal metastases will increase, and their related complications will increase unavoidably. Furthermore, considering the high complication rates reported in the spinal literature regarding spine surgery overall, it becomes clear that a better understanding of complications that the cancer patients with spinal metastases may experience is necessary. This article aims to summarize and critically examine the current evidence for complications after spine surgery for metastatic spinal disease, in both the perioperative and postoperative period. This paper would be useful for the treating physicians of these patients in their clinical practice.


Spine Surgery Metastasis Complications Survival Cancer 


Compliance with ethical standards

Conflict of interest

All authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag France SAS, part of Springer Nature 2019

Authors and Affiliations

  • Vasilios G. Igoumenou
    • 1
  • Andreas F. Mavrogenis
    • 2
    Email author
  • Andrea Angelini
    • 3
  • Riccardo Baracco
    • 3
  • Ahmed Benzakour
    • 4
  • Thami Benzakour
    • 5
  • Martin Bork
    • 1
  • Farzam Vazifehdan
    • 1
  • Ugo Nena
    • 3
  • Pietro Ruggieri
    • 3
  1. 1.Spine Center Stuttgart, Diakonie-Klinikum StuttgartStuttgartGermany
  2. 2.First Department of OrthopaedicsNational and Kapodistrian University of Athens, School of MedicineAthensGreece
  3. 3.Department of Orthopaedics and Musculoskeletal OncologyUniversity of PadovaPadovaItaly
  4. 4.Spinal Surgery OfficeClinique de l’ ArchetteOlivetFrance
  5. 5.Zerktouni Orthopaedic ClinicCasablancaMorocco

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