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Use of stem cells and growth factors in rotator cuff tendon repair

  • Dimitrios Tsekes
  • Georgios Konstantopoulos
  • Wasim S. Khan
  • Daniel Rossouw
  • Mike Elvey
  • Jagwant Singh
General Review • SHOULDER - BIOMATERIAL
  • 36 Downloads

Abstract

The management of rotator cuff tears continues to prove challenging for orthopaedic surgeons. Such tears affect most age groups and can lead to significant morbidity in patients. The aetiology of these tears is likely to be multifactorial; however, an understanding of the mechanisms involved is still under review. Despite advancements in surgical operative techniques and the materials used, post-operative recurrence rates after surgical repair remain high. A growing area of research surrounds biological adjuncts used to improve the healing potential of the repaired tissues. This review of recent publications focuses on the strengths and limitations of using stem cells and growth factors in rotator cuff repair.

Keywords

Rotator cuff tears Mesenchymal stem cells Growth factors 

Notes

Acknowledgements

The authors confirm that no funds were received in support of this study and no benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Human and animal rights

This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer-Verlag France SAS, part of Springer Nature 2019

Authors and Affiliations

  • Dimitrios Tsekes
    • 1
  • Georgios Konstantopoulos
    • 2
  • Wasim S. Khan
    • 1
  • Daniel Rossouw
    • 3
  • Mike Elvey
    • 4
  • Jagwant Singh
    • 1
  1. 1.Barnet General Hospital, Royal Free NHS Foundation TrustLondonUK
  2. 2.Royal Derby Hospital, Derby Teaching HospitalsDerbyUK
  3. 3.Shoulder UnitBarnet General Hospital, Royal Free NHS Foundation TrustLondonUK
  4. 4.Writtington HospitalWrittingtonUK

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