European Spine Journal

, Volume 28, Issue 7, pp 1610–1617 | Cite as

Dextrose injections for failed back surgery syndrome: a consecutive case series

  • İlker Solmaz
  • Serkan Akpancar
  • Aydan Örsçelik
  • Özlem Yener-KarasimavEmail author
  • Deniz Gül
Original Article



Patients with chronic low back pain, who do not respond to conservative treatment methods, generally undergo surgical revision operations, and sometimes an undesirable condition called failed back surgery syndrome (FBSS) may be inevitable. Hereby, dextrose is one of the regenerative methods that has gained popularity in the treatment of many musculoskeletal problems, and we aimed to present and evaluate the outcomes of 5% dextrose for the treatment of FBSS.


It has been designed as a consecutive case series. A total of 79 patients with FBSS, who had minimum 6 months of symptoms and did not respond to 3 months of conservative methods between May 2014 and March 2016, participated in the study. Prolotherapy injections were applied in posterior and lateral approaches. Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) were used for the pre- and post-treatment evaluations. Patient satisfaction was assessed with using a 5-point Likert scale by phone contacting.


There was statistically significant difference between repeated VAS and ODI measurements.


These results may be the first step giving a lead to an undiscovered field. This treatment method should be kept in mind for FBSS patients before giving a decision of revision surgery.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.


Failed back surgery syndrome FBSS Prolotherapy Dextrose Injection 



We all thank Michael Yelland, Associate Professor, MD, and John Lyftogt, MD, for their respected contributions to the designation of this paper.

Compliance with ethical standards

Conflict of interest

İlker Solmaz, Serkan Akpancar, Aydan Örsçelik, Özlem Yener-Karasimav and Deniz Gül declare that they have no conflict of interest.

Supplementary material

586_2019_6011_MOESM1_ESM.pptx (153 kb)
Supplementary file1 (PPTX 152 kb)


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Gulhane Training and Research Hospital, Traditional and Complementary Medicine Practice CenterUniversity of Health SciencesAnkaraTurkey
  2. 2.Orthopaedics and Traumatology ClinicsTokat State HospitalTokatTurkey
  3. 3.Gulhane Training and Research Hospital, Department of Sports MedicineUniversity of Health SciencesAnkaraTurkey

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