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Early versus delayed decompression for traumatic cervical spinal cord injury: application of the AOSpine subaxial cervical spinal injury classification system to guide surgical timing

  • Jin-Peng Du
  • Yong Fan
  • Jia-Nan Zhang
  • Ji-Jun Liu
  • Yi-Bin Meng
  • Ding-Jun HaoEmail author
Original Article

Abstract

Purpose

Application of AOSpine subaxial cervical spine injury classification system to explore the optimal surgical decompression timing for different types of traumatic cervical spinal cord injury (CSCI).

Methods

A single-center prospective cohort study was conducted that included patients with traumatic CSCIs (C3–C7) between February 2015 and October 2016. After enrollment, patients underwent either early (< 72 h after injury) or late (≥ 72 h after injury) decompressive surgery of the cervical spinal cord. Each group was divided into A0, A1-4, B, C/F4 and F1-3 subgroups. The primary outcomes were ordinal changes in the ASIA Impairment Scale (AIS) and the Spinal Cord Independence Measure III (SCIM version 3) at a 12-month follow-up. The secondary outcomes included length of hospital stay, postoperative neurological deterioration, other complications and mortality.

Results

A total of 402 patients were included. Of these, 187 patients underwent early decompression surgery, and 215 patients underwent delayed decompression surgery. Statistical results included the following comparisons of the early vs late groups: AIS improvement ≥ 1 grade (combined groups: P < 0.0001; A0: P = 0.554; A1-4: P = 0.084; B: P = 0.013; C/F4: P = 0.040; F1-3: P = 0.742); AIS improvement ≥ 2 grades, P = 0.003 for all groups; SCIM version 3 (combined groups: P < 0.0001; A0: P = 0.126; A1-4: P = 0.912; B: P = 0.006; C/F4: P = 0.111; F1-3: P = 0.875).

Conclusion

Type A and F1-3 fractures are not required to undergo aggressive early decompression. Type B and type C/F4 fractures should receive early surgical treatment for better clinical outcomes.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.

Keywords

Timing Cervical spinal cord injury AOSpine Surgical decompression 

Notes

Funding

No funds were received in support of this work.

Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest to declare.

Supplementary material

586_2019_5959_MOESM1_ESM.pdf (98 kb)
Supplementary material 1 (PDF 98 kb)
586_2019_5959_MOESM2_ESM.pptx (665 kb)
Supplementary material 2 (PPTX 665 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Jin-Peng Du
    • 1
    • 2
  • Yong Fan
    • 1
  • Jia-Nan Zhang
    • 1
  • Ji-Jun Liu
    • 1
  • Yi-Bin Meng
    • 1
  • Ding-Jun Hao
    • 1
    • 2
    Email author
  1. 1.Department of Spine SurgeryHong Hui Hospital, Xi’an Jiaotong UniversityXi’anChina
  2. 2.Medical CollegeYan’an UniversityYan’anChina

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