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Anterior controllable antedisplacement fusion as a choice for 28 patients of cervical ossification of the posterior longitudinal ligament with dura ossification: the risk of cerebrospinal fluid leakage compared with anterior cervical corpectomy and fusion

  • Haisong Yang
  • Jingchuan Sun
  • Jiangang Shi
  • Yongfei Guo
  • Bing Zheng
  • Yuan Wang
  • Ximing Xu
  • Guodong Shi
Original Article

Abstract

Purpose

To compare the incidence rate of cerebrospinal fluid (CSF) leakage between anterior controllable antedisplacement fusion (ACAF) and anterior cervical corpectomy and fusion (ACCF) in the treatment of ossification of the posterior longitudinal ligament (OPLL) with dura ossification (DO).

Methods

In the period from June 2015 to June 2017, ACAF and ACCF were performed on patients with OPLL with DO. Double-layer sign was observed on axial bone window of CT images. The operation duration, blood loss, and hospital stay were measured. Radiologic assessment included occupying rate, type and extent of OPLL, decompression width, postoperative area of the spinal canal, and anteroposterior diameter of the spinal cord. The JOA scoring system was used to evaluate the neurological status. Surgery-related complications such as CSF leakage and spinal cord or nerve injury were all recorded.

Results

There were 28 patients in ACAF group and 31 in ACCF group. On cross-sectional CT, decompression width and postoperative spinal canal area were both significantly larger in the ACAF group than that in the ACCF group (P < 0.01). The anteroposterior diameter of the spinal cord was significantly larger in the ACAF group (P < 0.05). Mean JOA score was better in the ACAF group (P < 0.05). In the ACCF group, seven (22.6%) patients had CSF leakage. However, only one (3.6%) presented with CSF leakage in the ACAF group. The difference of incidence rate of CSF leakage was significant (P < 0.01).

Conclusions

ACAF, which can significantly reduce CSF leakage and achieve good neurological recovery, is a good option to treat cervical OPLL with DO.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.

Keywords

Ossification of the posterior longitudinal ligament (OPLL) Anterior controllable antedisplacement fusion (ACAF) Anterior corpectomy and fusion (ACCF) Dural ossification (DO) Cerebrospinal fluid leakage Double-layer sign 

Notes

Funding

This study was supported by grants from the National Natural Science Foundation of China (No. 81650031). The manuscript submitted does not contain information about medical device(s)/drug(s).

Compliance with ethical standards

Conflict of interest

None of the authors has any potential conflict of interest.

Supplementary material

586_2018_5813_MOESM1_ESM.pptx (441 kb)
Electronic supplementary material 1 (PPTX 441 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Haisong Yang
    • 1
  • Jingchuan Sun
    • 1
  • Jiangang Shi
    • 1
  • Yongfei Guo
    • 1
  • Bing Zheng
    • 1
  • Yuan Wang
    • 1
  • Ximing Xu
    • 1
  • Guodong Shi
    • 1
  1. 1.Department of Orthopedics, Changzheng HospitalSecond Military Medical UniversityShanghaiChina

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