European Spine Journal

, Volume 27, Supplement 3, pp 520–525 | Cite as

Extensive spinal extradural ganglioneuroma of the lumbar spine: mimicking lymphoma

  • Seung Hun Kang
  • Sang Min LeeEmail author
  • Doo Hoe Ha
  • Hye Jin Lee
Case Report



Ganglioneuromas are rare, benign, well-differentiated tumors arising from neural crest cells that commonly occur in the posterior mediastinum, retroperitoneum, cervical spine, and adrenal gland. We report an unusual case of an extensive spinal extradural ganglioneuroma, circumferentially and longitudinally affecting the extradural space of the lumbar spine and continuously invading bilateral psoas muscles.

Case description

A 32-year-old man presented with a 1-week history of abdominal pain and diarrhea. Radiographs revealed scalloping of the posterior surfaces of the L2 and L3 vertebral bodies and widening of L2–3 and L3–4 bilateral intervertebral foramina. Computed tomography scans and magnetic resonance imaging showed a well-defined lobulated extradural mass from L1 to L4 and a continuously forming mass in the psoas muscles through L2–3 bilateral neural foramina. The mass demonstrated homogeneously isointense signal on T1-weighted images, inhomogeneously hyperintense-to-isointense signal on T2-weighted images, and inhomogeneous enhancement on fat-suppressed contrast-enhanced T1-weighted images. Radiologic diagnosis included spinal epidural lymphoma. Percutaneous biopsy with sonographic guidance was performed, and the mass was diagnosed on pathological examination as a ganglioneuroma.


This is the first known reported case in the literature of a spinal extradural ganglioneuroma with circumferentially and longitudinally extensive involvement of the extradural space and a large psoas mass.


Ganglioneuroma Extradural Spinal tumor Lumbar spine Lymphoma 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Radiology, CHA Bundang Medical CenterCHA University, School of MedicineSeongnam-siRepublic of Korea
  2. 2.Department of Pathology, CHA Bundang Medical CenterCHA University, School of MedicineSeongnam-siRepublic of Korea

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