Type V osteogenesis imperfecta undergoing surgical correction for scoliosis

  • Morgan Jones
  • Lee Breakwell
  • Ashley Cole
  • Paul Arundel
  • Nick Bishop
Grand Rounds


Open image in new windowPurpose

The objective of this article is to report a case of type V osteogenesis imperfecta (OI) undergoing posterior instrumented fusion for scoliosis. Type V OI is a moderately severe dysplasia causing primary defects in endochondral bone ossification or mineralisation. It is characterised by hyperplastic callus (HPC) formation, interosseous membrane calcifications, poor bone quality and spinal deformities including scoliosis. Data on the surgical management of spinal deformities in this patient group are lacking.

Case report

A 16-year-old patient with a confirmed diagnosis of type V OI presented with a progressive scoliosis. The patient underwent a T3–L4 posterior instrumented correction and fusion utilising pedicle screws, pedicle hooks and sub-laminar wiring. At 4 months after surgery, the pedicle hooks pulled out and required partial metalwork removal after CT scanning confirmed bony union and no evidence of HPC formation. The patient was successfully discharged with satisfactory correction, confirmed bony union, no neurologic complication and absence of any hyperplastic callus formation.


Type V OI patients requiring surgical intervention for scoliosis correction can safely undergo posterior instrumented fusion using sublaminar wiring and pedicle hook/screw constructs without apparent risk of HPC formation around neural elements. Surgery in this patient group remains challenging due to the associated poor bone quality.

Level of evidence



Osteogenesis imperfecta Type V Scoliosis Surgery Hyperplastic ossification 


Compliance with ethical standards

Conflict of interest

None of the authors has any potential conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Morgan Jones
    • 1
  • Lee Breakwell
    • 1
  • Ashley Cole
    • 1
  • Paul Arundel
    • 1
  • Nick Bishop
    • 1
  1. 1.Sheffield Children’s HospitalSheffieldUK

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