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European Spine Journal

, Volume 27, Issue 6, pp 1358–1364 | Cite as

Implantation of an empty polyetheretherketone cage in anterior cervical discectomy and fusion: a prospective randomised controlled study with 2 years follow-up

  • Shang-Wen Feng
  • Ming-Chau Chang
  • Po-Hsin Chou
  • Hsi-Hsien Lin
  • Shih-Tien Wang
  • Chien-Lin Liu
Original Article
  • 331 Downloads

Abstract

Purpose

To compare the clinical outcomes, radiographic results and fusion rate of ACDF between empty PEEK cages and PEEK cages packed with β-tricalcium phosphate.

Methods

Forty-five patients were prospectively enrolled with cervical degenerative disc disease who requiring ACDF with a PEEK cage. 23 patients were randomised to the study group (empty cages) and 22 patients were in the control group (cages filled with β-tricalcium phosphate). Both patient groups were fixed with a cervical locking plate. A CT scan was performed 12 months postoperatively and 24 months if not confirmed fused at 12 months to evaluate the status of fusion. Clinical status was evaluated using the Japanese Orthopaedic Association (JOA) score, the Oswestry Disability Index (ODI) and the Visual Analogue Scale (VAS).

Results

46 levels (97.88%) in the study group and 44 levels (97.77%) in the control group were confirmed as fused at 24 months. There was no significant difference between the fusion rates observed in the study and control groups (p = 0.82). There was no significant difference in JOA, ODI, or VAS scores at 24 months follow-up. The results showed that the members of the non-fusion group tended to be older than the individuals in the fusion group at 12 months, but was not significant in statistics.

Conclusions

Similar fusion rates and clinical outcomes were achieved when using ACDF with PEEK cages and instrumentation, regardless of whether the cage was filled with bone substitute at 24 months follow-up. Fusion rates improved over time and are comparable between both groups.

Graphical abstract

These slides can be retrieved under Electronic Supplementary material.

Keywords

Empty cage ACDF PEEK cage 

Notes

Acknowledgements

The study was supported by Division of Spine Surgery, Orthopaedic Department, Taipei Veterans General Hospital. We thank Hsin-Yi Huang from the Biostatistics Task Force, Taipei Veterans General Hospital, for the statistical assistance.

Compliance with ethical standards

Conflict of interest

None of the authors has any potential conflict of interest.

Supplementary material

586_2017_5450_MOESM1_ESM.pptx (259 kb)
Supplementary material 1 (PPTX 258 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Shang-Wen Feng
    • 1
    • 2
    • 3
  • Ming-Chau Chang
    • 1
    • 2
  • Po-Hsin Chou
    • 1
    • 2
  • Hsi-Hsien Lin
    • 1
    • 2
  • Shih-Tien Wang
    • 1
    • 2
  • Chien-Lin Liu
    • 1
    • 2
  1. 1.Department of Orthopedics and TraumatologyTaipei Veterans General HospitalTaipeiTaiwan, ROC
  2. 2.School of MedicineNational Yang-Ming UniversityTaipeiTaiwan, ROC
  3. 3.Department of OrthopedicsNational Yang-Ming University HospitalYilanTaiwan, ROC

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