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Spinal Taenia solium cysticercosis in Mexican and Indian patients: a comparison of 30-year experience in two neurological referral centers and review of literature

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Abstract

Objective

To present a retrospective study from patients with spinal cysticercosis (SC), diagnosed within the last 30 years in Mexican and Indian neurological referral centers.

Methods

This is a retrospective and comparative study of the clinical and radiological profile between Mexican and Indian patients with spinal neurocysticercosis during a 30-year period and a review of the literature during the same period.

Results

Twenty-seven SC patients were included: 19 from Mexico and 8 from India. SC presented predominantly with motor symptoms (21/27 patients): paraparesis and paraplegia were the most common signs; one-third of patients presented sphincter dysfunction. Imaging studies showed that parasites in vesicular stage were more frequent in patients from Mexico, while degenerative stages predominated in India. Association of subarachnoid cysticerci and hydrocephalus was observed only in Mexican patients.

Conclusions

Despite the limitations of this study, the collected information supports the existence of differences in the clinical and radiological traits of SC patients between Asian and Latin-American hospitals. The possible biological factors that may underlie these differences are discussed.

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Acknowledgements

Authors thank Juan Francisco Rodriguez for proofreading the English version of this manuscript.

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Authors and Affiliations

  1. Department of Neuroinfectology, Instituto Nacional de Neurología y Neurocirugía, Mexico City, Mexico

    Graciela Cárdenas, Erik Guevara-Silva, Felipe Romero, Yair Ugalde & José Luis Soto-Hernández

  2. Department of Neurology, Pitié-Salpêtrière Hospital, Paris, France

    Cecilia Bonnet

  3. Department of Immunology, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico City, Mexico

    Agnes Fleury & Edda Sciutto

  4. Universidade Estadual Paulista, Arçatuba, Brazil

    Caris Maroni Nunes

  5. National Institute of Mental Health and Neurosciences, Bangalore, India

    Susarla Krishna Shankar & Anita Mahadevan

  6. Department of Infectious Diseases, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Insurgentes Sur 3877, Tlalpan, CP. 14269, Mexico, D.F., Mexico

    Graciela Cárdenas

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  1. Graciela Cárdenas
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Cárdenas, G., Guevara-Silva, E., Romero, F. et al. Spinal Taenia solium cysticercosis in Mexican and Indian patients: a comparison of 30-year experience in two neurological referral centers and review of literature. Eur Spine J 25, 1073–1081 (2016). https://doi.org/10.1007/s00586-015-4271-9

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