Advertisement

European Spine Journal

, Volume 20, Supplement 2, pp 309–313 | Cite as

Kaposiform hemangioendothelioma with adolescent thoracic scoliosis: a case report and review of literature

  • Yong Zhu
  • Guixing QiuEmail author
  • Hong Zhao
  • Jinqian Liang
  • Xiaohua Shi
Case Report

Abstract

Kaposiform hemangioendothelioma (KHE) is a rare locally aggressive vascular tumor that usually presents as a superficial or deep soft tissue mass with associated cutaneous lesions. We report a unique spinal KHE with painless thoracic scoliosis in a 14-year-old girl. She underwent simultaneous tumor biopsy, spinal deformity correction and fusion. At 3 years follow-up, the patient’s MRI showed no significant deterioration of process without any therapy. KHE presenting as scoliosis is rare and to our knowledge this is the first recognized case in the reported world literature.

Keywords

Kaposiform hemangioendothelioma Scoliosis Treatment 

Notes

Conflict of interest

None of the authors has any potential conflict of interest.

References

  1. 1.
    Gruman A, Liang MG, Mulliken JB et al (2005) Kaposiform hemangioendothelioma without Kasabach–Merritt phenomenon. J Am Acad Dermatol 52:616–622PubMedCrossRefGoogle Scholar
  2. 2.
    Lyons LL, North PE, Mac-Moune Lai F et al (2004) Kaposiform hemangioendothelioma: a study of 33 cases emphasizing its pathologic, immunophenotypic, and biologic uniqueness from juvenile hemangioma. Am J Surg Pathol 28:559–568PubMedCrossRefGoogle Scholar
  3. 3.
    DeFatta RJ, Verret DJ, Adelson RT et al (2005) Kaposiform hemangioendothelioma: case report and literature review. Laryngoscope 115:1789–1792PubMedCrossRefGoogle Scholar
  4. 4.
    Lai FM, Allen PW, Yuen PM et al (1991) Locally metastasizing vascular tumor. Spindle cell, epithelioid, or unclassified hemangioendothelioma? Am J Clin Pathol 96:660–663PubMedGoogle Scholar
  5. 5.
    Lalaji TA, Haller JO, Burgess RJ (2001) A case of head and neck kaposiform hemangioendothelioma simulating a malignancy on imaging. Pediatr Radiol 31:876–878PubMedCrossRefGoogle Scholar
  6. 6.
    Mac-Moune Lai F, To KF, Choi PC et al (2001) Kaposiform hemangioendothelioma: five patients with cutaneous lesion and long follow-up. Mod Pathol 14:1087–1092PubMedCrossRefGoogle Scholar
  7. 7.
    Zhou G, Yang S, Nie X et al (2007) Kaposiform hemangioendothelioma: case report and literature review. Chin J Clin Oncol 4:288–292CrossRefGoogle Scholar
  8. 8.
    Lisle JW, Bradeen HA, Kalof AN (2009) Kaposiform hemangioendothelioma in multiple spinal levels without skin changes. Clin Orthop Relat Res 467:2464–2471PubMedCrossRefGoogle Scholar
  9. 9.
    Zukerberg LR, Nickoloff BJ, Weiss SW (1993) Kaposiform hemangioendothelioma of infancy and childhood: an aggressive neoplasm associated with Kasabach–Merritt syndrome and lymphangiomatosis. Am J Surg Pathol 17:321–328PubMedCrossRefGoogle Scholar
  10. 10.
    Birchler MT, Schmid S, Holzmann D et al (2006) Kaposiform hemangioendothelioma arising in the ethmoid sinus of an 8-year-old girl with severe epistaxis. Head Neck 28:761–764PubMedCrossRefGoogle Scholar
  11. 11.
    Cooper JG, Edwards SL, Holmes JD (2002) Kaposiform hemangioendothelioma: case report and review of the literature. Br J Plast Surg 55:163–165PubMedCrossRefGoogle Scholar
  12. 12.
    Weiss SW, GoldbIum JR (eds) (2001) Enzinger and Weiss’s Soft Tissue Tumors, 4th edn. Mosby-Harcourt Brace, Philadelphia, pp 891–915Google Scholar
  13. 13.
    Hu B, Lachman R, Phillips J et al (1998) Kasabach–Merritt syndrome-associated kaposiform hemangioendothelioma successfully treated with cyclophosphamide, vincristine, and actinomycin D. J Pediatr Hematol Oncol 20:567–569PubMedCrossRefGoogle Scholar
  14. 14.
    Goldberg CJ, Moore DP, Fogarty EE et al (1999) Left thoracic curve patterns and their association with disease. Spine 24:1228–1233PubMedCrossRefGoogle Scholar
  15. 15.
    Aydinli U, Ozturk C, Ersozlu S et al (2003) Results of surgical treatment of osteoid osteoma of the spine. Acta Orthop Belg 69:350–354PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Yong Zhu
    • 1
  • Guixing Qiu
    • 2
    Email author
  • Hong Zhao
    • 2
  • Jinqian Liang
    • 2
  • Xiaohua Shi
    • 3
  1. 1.Department of Orthopedic SurgeryThe First Affiliated Hospital of Chongqing Medical UniversityChongqingChina
  2. 2.Department of Orthopedic Surgery, Peking Union Medical College HospitalChinese Academy of Medical Science & Peking Union Medical CollegeBeijingChina
  3. 3.Department of Pathology, Peking Union Medical College HospitalChinese Academy of Medical Science & Peking Union Medical CollegeBeijingChina

Personalised recommendations