The aging spine: new technologies and therapeutics for the osteoporotic spine
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- Lane, J.M., Gardner, M.J., Lin, J.T. et al. Eur Spine J (2003) 12(Suppl 2): S147. doi:10.1007/s00586-003-0636-6
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Osteoporosis results in low-energy fractures of the spine. The load necessary to cause a vertebral fracture is determined by the characteristics related to the vertebral body structure, mineral content, and quality of bone. Radiographic techniques centered on dual X-ray absorptiometry (DXA) permit a determination of bone mass and fracture risk. Current medical therapies principally using bisphosphonate and pulsatile PTH profoundly decrease the risk of fracture (50+%). Fall prevention strategies can further decrease the possibility of fracture. A comprehensive approach to osteoporosis can favorably alter the disease.