The use of copaiba oil in broiler chicks feed to replace antibiotic caused an anti-inflammatory effect and promoted weight gain
- 108 Downloads
The objective of this study was to assess the effect of copaiba oils (Copaifera reticulata and Copaifera duckei) on the health and performance of broiler chicks along with their anti-inflammatory activity. The experiment was performed in duplicate, using 60 chicks at a time. Groups were formed by broiler chicks fed with basal diet (control); basal diet and antibiotic (zinc bacitracin, 25 mg/kg of feed); basal diet and copaiba oil (0.15 mL/kg of feed); and basal diet and copaiba oil (0.30 mL/kg of feed) for 15 days. Sampling was performed on days 7 and 15 of life. Animals treated with 0.15 mL/kg of copaiba showed higher body weight (p < 0.05). The addition of copaiba oil in the diet caused a reduction in total leukocytes, mainly due to a reduction of lymphocytes (p < 0.001). Biochemical variables, such as total protein, albumin, globulin, cholesterol, and uric acid, did not differ between groups (p > 0.05); however, glucose and triglyceride levels were reduced on days 7 and 15 in animals that received copaiba oil, respectively (p < 0.05). No histopathological lesions were observed in the jejunum of all groups. Crypt and villus sizes were lower in animals treated with 0.15 mL/kg of copaiba oil. It is possible to conclude that copaiba vegetable oil at a dose of 0.15 mL/kg improved body weight gain and have anti-inflammatory effect.
KeywordsPoultry farming Copaifera redice reticulate Copaifera duckei Supplementation Animal production Hemogram Immune response
We thank Aurora who provided the chicks for this study.
Compliance with ethical standards
This experiment was approved by the Animal Welfare Committee of the State University of Santa Catarina (UDESC) under protocol number 9784300517.
Conflict of interest
The authors declare that they have no conflict of interest.
- Acree T, Heinrich A (2017) Flavornet and human odor space, URL http: www.flavornet.org
- Caruso M, Demonte A (2005) Histomorfometria do intestino delgado de ratos submetidos a diferentes fontes proteicas. Alim Nutr 16:131–136Google Scholar
- Custódio DL, Veiga VF (2012) True and common balsams. Rev Bras Farmacogn:221–215Google Scholar
- El-Sayed AM (2017) The pherobase. Database of pheromones and semiochemicals. http://www.pherobase.com
- FAO. Food and Agriculture Organization Of The United Nations Rome (2011) Drivers, dynamics and epidemiology of antimicrobial resistance in animal production. Available: http://www.fao.org/3/a-i6209e.pdf
- Ferreira LA (1999) Potencial de extração e comercialização do óleo-resina de copaíba (Copaifera spp.): um estudo de caso na Floresta Estadual do Antimary, Acre. São Carlos. Dissertação de Mestrado, Ecologia e Manejo de Recursos Naturais, Universidade Federal de São CarlosGoogle Scholar
- Ghoshal UC, Mehrotra M, Kumar S, Ghoshal U, Krishnani N, Misra A, Aggarwal R, Choudhuri G (2012) Spectrum of malabsorption syndrome among adults & factors differentiating celiac disease & tropical malabsorption. Indian J Med Res 136(3):451–459Google Scholar
- Kabploy K, Bunyapraphatsara N, Morales NP, Paraksa N (2016) Effect of antibiotic growth promoters on anti-oxidative and anti-inflammatory activities in broiler chickens. Thai J Vet Med 46:89–95Google Scholar
- Leite A (2001) Recomendações para o manejo sustentável do óleo de copaíba. Universidade Federal do Acre, Rio BrancoGoogle Scholar
- Leite NF, Sobral-Souza CE, Albuquerque RS, Brito DIV, Lavor A, Alencar L et al (2013) Actividad antiparasitaria in vitro citotóxica de cariofileno y eugenol contra Trypanosoma cruzi y Leishmania brasiliensis. Rev Cubana Plant Med 18:522–528Google Scholar
- Menten JFM (2001) Aditivos alternativos na produção de aves: probióticos e prebióticos. In: Reunião da Sociedade Brasileira de Zootecnia, 38., 2001, Piracicaba. Anais … Piracicaba: Sociedade Brasileira de Zootecnia, 141–157Google Scholar
- Rigamonte-Azevedo OC, Wadt PG, Wadt LH (2004) Copaíba: ecologia e produção de óleo-resina. EMBRAPA, MAPA, Rio BrancoGoogle Scholar
- Rostagno HS, Albino LFT, Donzele JL, Gomes PC, Oliveira RF, Lopes DC et al (2011) Tabelas brasileiras para aves e suínos: composição de alimentos e exigências nutricionais de aves e suínos, 3rd edn. UFV, Viçosa, p 252Google Scholar
- Thrall MA, Weiser G, Alisson RW, Campbell TW (2015) Hematologia e Bioquímica Clínica Veterinária, editora Roca, 2ed:688Google Scholar
- Wickham H (2009) Elegant graphics for data analysis. Springer, New YorkGoogle Scholar