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The use of copaiba oil in broiler chicks feed to replace antibiotic caused an anti-inflammatory effect and promoted weight gain

  • Luiz Gustavo Griss
  • Aleksandro S. da Silva
  • Gabriela M. Galli
  • Bruno F. Fortuoso
  • Gabriela Campigotto
  • Antonise M. Jaguezeski
  • Carine F. Souza
  • Mariane B. Fagundes
  • Roger Wagner
  • Anderson Gris
  • Ricardo E. Mendes
  • Marcel M. Boiago
  • Elaine C. P. Oliveira
  • Lenita M. Stefani
  • Gustavo Machado
Original Article
  • 60 Downloads

Abstract

The objective of this study was to assess the effect of copaiba oils (Copaifera reticulata and Copaifera duckei) on the health and performance of broiler chicks along with their anti-inflammatory activity. The experiment was performed in duplicate, using 60 chicks at a time. Groups were formed by broiler chicks fed with basal diet (control); basal diet and antibiotic (zinc bacitracin, 25 mg/kg of feed); basal diet and copaiba oil (0.15 mL/kg of feed); and basal diet and copaiba oil (0.30 mL/kg of feed) for 15 days. Sampling was performed on days 7 and 15 of life. Animals treated with 0.15 mL/kg of copaiba showed higher body weight (p < 0.05). The addition of copaiba oil in the diet caused a reduction in total leukocytes, mainly due to a reduction of lymphocytes (p < 0.001). Biochemical variables, such as total protein, albumin, globulin, cholesterol, and uric acid, did not differ between groups (p > 0.05); however, glucose and triglyceride levels were reduced on days 7 and 15 in animals that received copaiba oil, respectively (p < 0.05). No histopathological lesions were observed in the jejunum of all groups. Crypt and villus sizes were lower in animals treated with 0.15 mL/kg of copaiba oil. It is possible to conclude that copaiba vegetable oil at a dose of 0.15 mL/kg improved body weight gain and have anti-inflammatory effect.

Keywords

Poultry farming Copaifera redice reticulate Copaifera duckei Supplementation Animal production Hemogram Immune response 

Notes

Acknowledgements

We thank Aurora who provided the chicks for this study.

Compliance with ethical standards

This experiment was approved by the Animal Welfare Committee of the State University of Santa Catarina (UDESC) under protocol number 9784300517.

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag London Ltd., part of Springer Nature 2018

Authors and Affiliations

  • Luiz Gustavo Griss
    • 1
  • Aleksandro S. da Silva
    • 1
    • 2
    • 3
  • Gabriela M. Galli
    • 2
  • Bruno F. Fortuoso
    • 1
  • Gabriela Campigotto
    • 2
  • Antonise M. Jaguezeski
    • 2
  • Carine F. Souza
    • 3
  • Mariane B. Fagundes
    • 4
  • Roger Wagner
    • 4
  • Anderson Gris
    • 5
  • Ricardo E. Mendes
    • 5
  • Marcel M. Boiago
    • 1
    • 2
  • Elaine C. P. Oliveira
    • 6
  • Lenita M. Stefani
    • 1
    • 2
  • Gustavo Machado
    • 7
  1. 1.Departamento de ZootecniaUniversidade do Estado de Santa CatarinaChapecóBrazil
  2. 2.Programa de Pós-graduação em Zootecnia, UDESCChapecóBrazil
  3. 3.Programa de Pós-graduação em Bioquímica ToxicológicaUniversidade Federal de Santa Maria (UFSM)Santa MariaBrazil
  4. 4.Programa de Pós-graduação em Tecnologia de AlimentosUFSMSanta MariaBrazil
  5. 5.Laboratório de Patologia VeterináriaInstituto Federal CatarinenseConcórdiaBrazil
  6. 6.Universidade Federal do Oeste do ParáSantarémBrazil
  7. 7.Department of Population Health and Pathobiology, College of Veterinary MedicineNorth Carolina State UniversityRaleighUSA

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