Proteomic impacts of electromagnetic fields on the male reproductive system
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The use of mobile phones and other wireless transmitting devices is increasing dramatically in developing and developed countries, as is the rate of infertility. A number of respected infertility clinics in Australia, India, USA, and Iran are reporting that those who regularly use mobile phones tend to have reduced sperm quantity and quality. Some experimental studies have found that human sperm exposed to electromagnetic fields (EMF), either simulated or from mobile phones, developed biomarkers of impaired structure and function, as well as reduced quantity. These encompass pathological, endocrine, and proteomic changes. Proteins perform a vast array of functions within living organisms, and the proteome is the entire array of proteins—the ultimate biomolecules in the pathways of DNA transcription to translation. Proteomics is the art and science of studying all proteins in cells, using different techniques. This paper reviews proteomic experimental and clinical evidence that EMF acts as a male-mediated teratogen and contributor to infertility.
KeywordsProteome Mobile phone Electromagnetic Male-mediated teratogen Blood-testis-barrier Heat-shock proteins
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Conflict of interest
The authors declare that they have no conflict of interest.
Research involving human participants and/or animals
This article does not contain any studies with human participants or animals performed by any of the authors.
Due to the nature of review paper, no informed consent was available.
- Afshari F, Soleimani Rad J, Torabi GA, Yasrebi B (2013) Effects of electromagnetic field on the ductus deferent and prostate. Urmia Med J 24:527–533Google Scholar
- Akdag MZ, Dasdag S, Aksen F, Isik B, Yilmaz F (2006) Effect of ELF magnetic fields on lipid peroxidation, sperm count, p53, and trace elements. Med Sci Monit 12:366–371Google Scholar
- Barrett KE, Barman SM, Boitano S, Brooks H (2012) Ganong’s review of medical physiology, 24th edn., McGraw Hill ProfessionalGoogle Scholar
- Kesari KK, Kumar S, Behari J (2010) Mobile phone usage and male infertility in Wistar rats Indian. J Exp Biol 48:987–992Google Scholar
- Malmstrom E, Kilsgard O, Hauri S, Smeds E, Herwald H, Malmstrom L, Malmstrom J (2016) Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics. Nat Commun. 7. doi: 10.1038/ncomms10261.
- Mohammadi Roushandeh A, Halabian R, Mozafari P, Soleimani Rad J, Sadeghzadeh Oskouei B, Samadi Kuchaksaraei A, Habibi Roudkenar M (2009) Down-regulation of lipocalin 2 expression in mouse testis after exposure to electromagnetic field. Iran J Med Sci 34:265–270Google Scholar
- Parivar K, Nabiuni M, Golestanian N, Amini E (2011) Effect of low frecuency electromagnetic fields on the spermatogenesis and blood serum protein of Balb/c mice. J Cell Tissue 2:47–56Google Scholar
- Sepehrimanesh M (2016) Properties of probiotic bacteria: A proteomic approach. In: Watson RR, Preedy RR, editors. Probiotics, Prebiotics, and Synbiotics Bioactive Foods in Health Promotion. 2nd ed. Academic Press, pp 593–604Google Scholar