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Comparative Clinical Pathology

, Volume 21, Issue 5, pp 1065–1069 | Cite as

The prevalence of cutaneous leishmaniasis in school children in southwestern Iran, 2009

  • Hojat Asgari Nezhad
  • Mohammad Mirzaie
  • Iraj Sharifi
  • Mehdi Zarean
  • Mojtaba Norouzi
Original Article

Abstract

This study was designed to assess the epidemiological characteristics and molecular characterization of the disease in school children in the city of Dehloran, southwestern Iran. A total of 7,555 school children from the city of Dehloran were surveyed as a descriptive cross-sectional study during autumn 2009. A questionnaire was completed, recording demographic and disease characteristics. Microscopic examination and kinetoplast DNA-PCR assay were carried out for leishmaniasis detection and species identification. The overall prevalence of scars and active lesions were 9.7% and 0.4%, respectively. The prevalence rate of cutaneous leishmaniasis (CL) was significantly different between males and females (P < 0.05). The highest rate of CL was detected in the age group of 10–14 years with significant differences (P < 0.05). Most of the lesions were on face (42%). Clinically, 76.5% of the patients had single lesion. Also the prevalence rate in non-native residents was significantly higher than natives (P < 0.05). PCR technique revealed all examined cases as Leishmania major. CL in Dehloran is mainly caused by L. major and measures should be planned for future control programs. In addition, further investigations are required to clarify the possible reservoirs and vectors in the area.

Keywords

Cutaneous leishmaniasis Epidemiology Leishmania major Dehloran 

Notes

Acknowledgments

This paper is part of M.Sc. thesis. The authors would like to thank Mr. Valizadeh and the staff of the Veterinary Network of Dehloran county for their kind assistance.

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer-Verlag London Limited 2011

Authors and Affiliations

  • Hojat Asgari Nezhad
    • 1
    • 2
  • Mohammad Mirzaie
    • 3
  • Iraj Sharifi
    • 4
  • Mehdi Zarean
    • 4
  • Mojtaba Norouzi
    • 5
  1. 1.Student of Veterinary Parasitology, School of Veterinary MedicineShahid Bahonar University of KermanKermanIran
  2. 2.Young Researchers SocietyShahid Bahonar University of KermanKermanIran
  3. 3.Department of Pathobiology, School of Veterinary MedicineShahid Bahonar University of KermanKermanIran
  4. 4.Dermatology and Leishmaniasis Research CenterKerman University of Medical ScienceKermanIran
  5. 5.Razi Vaccine and Serum Research InstituteKarajIran

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