A novel numerical modeling paradigm for bio particle tracing in non-inertial microfluidics devices

  • Amirali Ebadi
  • Reihaneh Toutouni
  • Mohammad Javad Farshchi Heydari
  • Morteza Fathipour
  • Madjid Soltani
Technical Paper


In this work, we report on the design and implementation of a new method for the two dimensional (2D) simulation of rigid spherical particles trajectory which are to be separated in a microfluidics device based on their sizes. The advantages of efficient particle trajectory simulation method (EPTSM) include drastically smaller runtimes as compared with other methods as well as the ability to include particle collisions with channel’s walls and its ability to be extended to 3D simulations. Numerically simulated results were verified using a specifically designed and fabricated deterministic lateral displacement microfluidic device test structure. The method has provided realistic results for the study of multi-particles throughout the entire channel.



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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Amirali Ebadi
    • 1
  • Reihaneh Toutouni
    • 2
    • 3
  • Mohammad Javad Farshchi Heydari
    • 5
  • Morteza Fathipour
    • 1
    • 2
  • Madjid Soltani
    • 4
    • 5
  1. 1.MEMS and NEMS Laboratory, Department of Electrical and Computer Engineering, Faculty of EngineeringUniversity of TehranTehranIran
  2. 2.Device Simulation and Modeling Laboratory, Department of Electrical and Computer Engineering, Faculty of EngineeringUniversity of TehranTehranIran
  3. 3.Department of Petroleum EngineeringUniversity of WyomingLaramieUSA
  4. 4.Centre for Biotechnology and Bioengineering (CBB)University of WaterlooWaterlooCanada
  5. 5.Department of Mechanical EngineeringK. N. Toosi University of TechnologyTehranIran

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