Design of MEMS sensor for the detection of cholera and diarrehea by capacitance modulation
- 134 Downloads
Cholera is caused by vibriocholera bacteria which were present in water or food. Diarrhea is caused by E. coli bacteria which were present in water or food. Bio-sensors were used for the detection of waterborne elements in the fluids. This, paper provides a bio-sensor for the detection of cholera and diarrehea which is present in the water using capacitive technique. The bio-sensor is designed using FEM tool. Two types of channel based bio-sensor was designed cylindrical based and rectangular based. A simulation is also performed with and without the presence of bacteria cells in water and resultant capacitance is also computed using FEM tool. The sensitivity of the device is also calculated with and without the presence of bacteria cells in the water. The flow velocity, flow rate of cylindrical and rectangular channels is performed using FEM tool.
The Authors would like to thank to NMDC supported by NPMASS, National Institute of Technology, Silchar for providing the necessary computational tools. The corresponding author (Dr. K. Srinivasa Rao) would like to thank Science Engineering Research Board (SERB), Govt. of India, New Delhi (Grant File No: ECRA/2016/000757) for providing partial financial assistance to carry out this work.
- Dwivedi AK et al (2010) Detection of E. coli cell using capacitance modulation. COMSOL users conference Bengaluru, IndiaGoogle Scholar
- Baker RM, Singleton FL, Hood MA (1983) Appl Environ Microbiol 46(4):930–940Google Scholar
- Koch WH, Payne WL, Wentz BA, Cebula TA (1993) Appl Environ Microbiol 59(2):556–560Google Scholar
- Liuand Y, Duan Y (2006) Encyclopaedia of sensors, vol 1. American Scientific Publishers, New York, pp 371–400Google Scholar
- Lkojiasami et al Dielectric analysis of Escherichia coli suspensions in the light of the theory of interfacial polarization. Institute for Chemical Research, Kyoto University, Uji, Kyoto-fu 611, JapanGoogle Scholar
- Stender H et al (2001) Rapid detection, identification, and enumeration of Escherichia coli cells in municipal water by chemiluminescent in situ hybridization. Appl Environ Microbiol 67(1):9–10, 11, 142–147Google Scholar
- Weber M, Yerino C, Montanaro H, Lo KSL, Reed M (2001) Multiphysics simulations enable development of fast, cheap MEMS-based bacteria detector. Winner of 2011 create the future design contest aims at reducing food-borne infectionsGoogle Scholar
- Yoh M, Miyagi K, Matsumoto Y, Hayashi K, Takarada Y, Yamamoto K, Honda T (1993) Development of an enzyme-labeled oligonucleotide probe for the cholera toxin gene. J Clin Microbiol 31(5):1312–1314Google Scholar