Microsystem Technologies

, Volume 18, Issue 2, pp 151–158 | Cite as

Gold nanoparticle synthesis in microfluidic systems and immobilisation in microreactors designed for the catalysis of fine organic reactions

  • Ftouni Jamal
  • Girardon Jean-Sébastien
  • Penhoat Maël
  • Payen Edmond
  • Rolando Christian
Technical Paper

Abstract

Our work is focused on two applications of fine tunable microfluidic systems, first to optimize heterogeneous size nanoparticle synthesis and second to build catalytic microreactors for advanced organic reactions. The first part of our work consists in the use of an original microfluidic setup for gold nanoparticle synthesis, which allows a high control of the reaction parameters as the reactants flow, the concentration, the temperature, and the reaction time. We show that using such microfluidic systems permit a better control of the reaction parameters for producing homodispersed 1–2 nm gold nanoparticle. The second part of our work deals with the incorporation of gold nanoparticles into silica capillaries to build catalytic microreactors dedicated to fine chemical reactions. Our strategy consists in the immobilization of gold nanopadiegolirticles onto the inner surface (2D dispersion) or into the inner volume (3D dispersion) of functionalized silica microcapillaries. Characterizations show that by different functionalization procedures, those gold nanoparticles are well anchored inside the microcapillary.

Keywords

Gold Nanoparticles Capillary Tubing Constant Flow Rate Microfluidic System Aminopropyltriethoxy Silane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The authors thank the “Nord-Pas de Calais” region and the “CNRS” for the allocation of a “CNRS-BDI Thesis”, and the Chevreul federation (IMMCL) for it financial support (CPER). We gratefully thank Dr. Ahmed Addad (UMET, Lille) for his help for SEM/EPMA characterizations at the “Centre Commun de Microscopie de Lille” and Dr. Bastien Leger (UCCS, Lens) for his help for nanoparticles size determination with the DLS technique.

References

  1. Bogdan AR, Mason BP, Sylvester KT, McQuade DT (2007) Improving solid-supported catalyst productivity by using simplified packed-bed microreactors. Angew Chem Int Ed Engl 119:1728–1731CrossRefGoogle Scholar
  2. Diegoli S, Mendes PM, Baguley ER, Leigh SJ, Iqbal P, Diaz YRG, Begum S, Critchley K, Hammonds GD, Evans SD, Attwood D, Jones IP, Preece JA (2006) PH-Dependent gold nanoparticle self-organization on functionalized Si/SiO2 surfaces. J Exp Nanosci 1:333–353CrossRefGoogle Scholar
  3. Enüstün BV, Turkevich J (1963) Coagulation of Colloidal Gold. J Am Chem Soc 85:3317CrossRefGoogle Scholar
  4. Grace AN, Pandian K (2006) One pot synthesis of polymer protected gold nanoparticles and nanoprisms in glycerol. Colloids Surf A: Phys Eng Asp 290:138–142CrossRefGoogle Scholar
  5. Haruta M, Yamada N, Kobayashi T, Iijima S (1989) Gold catalysts prepared by coprecipitation for low-temperature oxidation of hydrogen and of carbon monoxide. J Catal 115(2):301–309CrossRefGoogle Scholar
  6. Kamat PV (2002) Photophysical, photochemical and photocatalytic aspects of metal nanoparticles. J Phys Chem B 106(32):7729–7744CrossRefGoogle Scholar
  7. Köhler JM, Abahmane L, Wagner J, Albert J, Mayer G (2008) Preparation of metal nanoparticles with varied composition for catalytical applications in microreactors. Chem Eng Sci 63:5048–5055CrossRefGoogle Scholar
  8. Le Gac S, Carlier J, Camart J-C, Cren-Olive C, Rolando C (2004) Monoliths for microfluidic devices in proteomics. J Chromatogr B 808:3–14CrossRefGoogle Scholar
  9. Lee KY, Hwang J, Lee YW, Kim J, Han SW (2007) One-step synthesis of gold nanoparticles using azacryptand and their applications in SERS and catalysis. J Colloid Interface Sci 316:476–481CrossRefGoogle Scholar
  10. Marre S, Jensen KF (2010) Synthesis of micro and nanostructures in microfluidic systems. Chem Soc Rev 39:1183–1202CrossRefGoogle Scholar
  11. Narayanan R, El-Sayed MA (2004) Shape-dependent catalytic activity of platinum nanoparticles in colloidal solution. Nano Lett 4:1343–1348CrossRefGoogle Scholar
  12. Polte J, Ahner T, Delissen F, Sokolov S, Thunemann AF, Kraehnert R (2010) mechanism of gold nanoparticle formation in the classical citrate synthesis method derived from coupled in situ XANES and SAXS evaluation. J Am Chem Soc 132:1296–1301CrossRefGoogle Scholar
  13. Sharma KK, Anan A, Buckley RP, Ouellette W, Asefa T (2008) Toward efficient nanoporous catalysts: controlling site-isolation and concentration of grafted catalytic sites on nanoporous materials with solvents and colorimetric elucidation of their site-isolation. J Am Chem Soc 130:218–228CrossRefGoogle Scholar
  14. Shi H, Xu N, Zhao D, Xu B-Q (2008) Immobilized PVA-stabilized gold nanoparticles on silica show an unusual selectivity in the hydrogenation of cinnamaldehyde. Catal Commun 9:1949–1954CrossRefGoogle Scholar
  15. Taton TA, Mirkin CA, Letsinger RL (2000) Scanometric DNA array detection with nanoparticle probes. Science 289:1757CrossRefGoogle Scholar
  16. Turkevich J, Stevenson PC, Hillier J (1953) The formation of colloidal gold. J Phys Chem 57:670–673CrossRefGoogle Scholar
  17. Wagner J, Kirner T, Mayerb G, Albert J, Köhler JM (2004) Generation of metal nanoparticles in a microchannel reactor. Chem Eng J 101:251–260CrossRefGoogle Scholar
  18. Wagner J, Kohler JM (2005) Continuous synthesis of gold nanoparticles in a microreactor. Nano Lett 4:685–691CrossRefGoogle Scholar
  19. Wang N, Matsumoto T, Ueno M, Miyamura H, Kobayashi S (2009) A gold-immobilized microchannel flow reactor for oxidation of alcohols with molecular oxygen. Angew Chem 48:4744–4746CrossRefGoogle Scholar
  20. Yang S-Y, Cheng F-Y, Yeh C-S, Lee G-B (2009) Size-controlled synthesis of gold nanoparticles using a micro-mixing system. Microfluid Nanofluid 8:303–311CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Ftouni Jamal
    • 1
    • 2
  • Girardon Jean-Sébastien
    • 1
  • Penhoat Maël
    • 2
  • Payen Edmond
    • 1
  • Rolando Christian
    • 2
  1. 1.Unité de Catalyse et de Chimie du Solide, UMR CNRS 8181Université Lille 1 Nord de France, Université des Sciences et Technologies de Lille Bâtiment C3Villeneuve d’Ascq CedexFrance
  2. 2.Miniaturisation pour l’Analyse, la Synthèse et la Protéomique, USR 3290Université Lille 1 Nord de France, Université des Sciences et Technologies de Lille Bâtiment C4Villeneuve d’Ascq CedexFrance

Personalised recommendations