Advertisement

Journal of Anesthesia

, 25:563 | Cite as

Stroke volume variation obtained with Vigileo/FloTrac™ system during bleeding and fluid overload in dogs

  • Hiroyuki Taguchi
  • Keisuke Ichinose
  • Hironari Tanimoto
  • Michiko Sugita
  • Masafumi Tashiro
  • Tatsuo Yamamoto
Original Article

Abstract

Purpose

Stroke volume variation (SVV) is a parameter for estimating fluid responsiveness. Recently, the Vigileo™ and the Flo-Trac™ sensor (Edwards Lifesciences, Irvine, CA, USA) were made available for clinical use to estimate SVV. The aim of this study was to investigate the relationship between the circulating blood volume and SVV, measured by the Vigileo-FloTrac™ system (SVV-FloTrac) or by central venous pressure (CVP), during a dynamic change in circulating blood transfusion volume, using a continuous constant bleeding and fluid-overload model in dogs.

Methods

Ten anesthetized and mechanically ventilated beagles were used. SVV-FloTrac and CVP were measured during a bleeding period (2 ml/kg/min, 15 min), a stabilization period (15 min), a blood transfusion period (2 ml/kg/min, 15 min), and a 6% hydroxyethyl starch solution overload period (2 ml/kg/min, 15 min).

Results

SVV-FloTrac changed significantly when more than 8 ml/kg blood was withdrawn or when more than 8 ml/kg blood was transfused. The change in SVV-FloTrac directly reflected the circulating blood volume change during continuous bleeding and blood transfusion. CVP decreased significantly when more than 4 ml/kg blood was withdrawn or when more than 10 ml/kg was infused, and this indicated that the CVP change did not directly reflect the level of the circulating blood volume change. During the stable circulating blood volume period after blood withdrawal, SVV-FloTrac changed significantly but CVP remained constant. During the fluid overload period, CVP, but not SVV-FloTrac, changed significantly.

Conclusion

SVV-FloTrac is a sensitive indicator of the dynamic circulating blood volume change during both bleeding and transfusion, but not during either the stable circulating blood volume period after blood withdrawal or the fluid-overload period, in mechanically ventilated dogs.

Keywords

Stroke volume Central venous pressure Circulating blood volume 

Notes

Acknowledgments

This study was supported by Kumamoto University, Kumamoto, Japan.

References

  1. 1.
    Bendjelid K, Romand J-A. Fluid responsiveness in mechanically-ventilated patients: a review of indices used in intensive care. Intensive Care Med. 2003;29:352–60.PubMedCrossRefGoogle Scholar
  2. 2.
    Michard F. Changes in arterial pressure during mechanical ventilation. Anesthesiology. 2005;103:419–28.PubMedCrossRefGoogle Scholar
  3. 3.
    Kumar A, Anel R, Bunnell E, Habet K, Zanotti S, Marshall S, Neumann A, Ali A, Cheang M, Kavinsky C, Parrillo JE. Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects. Crit Care Med. 2004;32:691–9.PubMedCrossRefGoogle Scholar
  4. 4.
    Grocott MP, Mythen MG, Gan TJ. Perioperative fluid management and clinical outcomes in adults. Anesth Analg. 2005;100:1093–106.PubMedCrossRefGoogle Scholar
  5. 5.
    Hofer CK, Senn A, Weibel L, Zollinger A. Assessment of stroke volume variation for prediction of fluid responsiveness using the modified FloTrac and PiCCOplus system. Crit Care. 2008;12:R82.PubMedCrossRefGoogle Scholar
  6. 6.
    Cannesson M, Musard H, Desebbe O, Boucau C, Simon R, Henaine R, Lehot J-J. The ability of stroke volume variations obtained with Vigileo/FloTrac system to monitor fluid responsiveness in mechanically ventilated patients. Anesth Analg. 2009;108:513–7.PubMedCrossRefGoogle Scholar
  7. 7.
    Fujita Y, Yamamoto T, Sano I, Yoshioka N, Hinenoya H. A comparison of changes in cardiac preload variables during graded hypovolemia and hypervolemia in mechanically ventilated dogs. Anesth Analg. 2004;99:1780–6.PubMedCrossRefGoogle Scholar
  8. 8.
    Berkenstadt H, Friedman Z, Preisman S, Keidan I, Livingstone D, Perel A. Pulse pressure and stroke volume variations during severe haemorrhage in ventilated dogs. Br J Anaesth. 2005;94:721–6.PubMedCrossRefGoogle Scholar
  9. 9.
    Biais M, Nouette-Gaulain K, Roullet S, Quinart A, Revel P, Sztark F. A comparison of stroke volume variation measured by Vigileo™/FloTrac™ system and aortic Doppler echocardiography. Anesth Analg. 2009;109:466–9.PubMedCrossRefGoogle Scholar
  10. 10.
    Biais M, Nouette-Gaulain K, Cottenceau V, Revel P, Sztark F. Uncalibrated pulse contour-derived stroke volume variation predicts fluid responsiveness in mechanically ventilated patients undergoing liver transplantation. Br J Anaesth. 2008;101:761–8.PubMedCrossRefGoogle Scholar
  11. 11.
    Drummond JC. MAC for halothane, enflurane, and isoflurane in the New Zealand white rabbit: and a test for the validity of MAC determinations. Anesthesiology. 1985;62:336–8.PubMedCrossRefGoogle Scholar
  12. 12.
    Pratt B, Roteliuk L, Hatib F, Frazier J, Wallen RD. Calculating arterial pressure-based cardiac output using a novel measurement and analysis method. Biomed Instrum Technol. 2007;41:403–11.PubMedCrossRefGoogle Scholar
  13. 13.
    Ganter MT, Hofer CK, Pittet JF. Postoperative intravascular fluid therapy. In: Miller RD, editor. Miller’s Anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2010. p. 2783–803.Google Scholar

Copyright information

© Japanese Society of Anesthesiologists 2011

Authors and Affiliations

  • Hiroyuki Taguchi
    • 1
  • Keisuke Ichinose
    • 1
  • Hironari Tanimoto
    • 1
  • Michiko Sugita
    • 1
  • Masafumi Tashiro
    • 1
  • Tatsuo Yamamoto
    • 1
  1. 1.Department of AnesthesiologyKumamoto University HospitalKumamotoJapan

Personalised recommendations